The polypharmacological effects of cannabidiol

J Castillo-Arellano, A Canseco-Alba, SJ Cutler, F León - Molecules, 2023 - mdpi.com
Cannabidiol (CBD) is a major phytocannabinoid present in Cannabis sativa (Linneo, 1753).
This naturally occurring secondary metabolite does not induce intoxication or exhibit the …

Cytokines and intestinal epithelial permeability: A systematic review

F Meyer, D Wendling, C Demougeot, C Prati… - Autoimmunity …, 2023 - Elsevier
Background The intestinal mucosa is composed of a well-organized epithelium, acting as a
physical barrier to harmful luminal contents, while simultaneously ensuring absorption of …

[HTML][HTML] The use of cannabinoids in the treatment of inflammatory bowel disease (IBD): a review of the literature

BN Nduma, KA Mofor, J Tatang, C Ekhator, S Ambe… - Cureus, 2023 - ncbi.nlm.nih.gov
Around the world, about 15 to 40% of individuals with inflammatory bowel disease (IBD) rely
on cannabis and cannabinoids to reduce the need for other medications, as well as increase …

The potential role of cannabinoids in dermatology

T Sheriff, MJ Lin, D Dubin… - Journal of Dermatological …, 2020 - Taylor & Francis
Cannabis is increasingly being used world-wide to treat a variety of dermatological
conditions. Medicinal cannabis is currently legalized in Canada, 31 states in America and 19 …

Cannabinoids in the pathophysiology of skin inflammation

C Scheau, IA Badarau, LG Mihai, AE Scheau… - Molecules, 2020 - mdpi.com
Cannabinoids are increasingly-used substances in the treatment of chronic pain, some
neuropsychiatric disorders and more recently, skin disorders with an inflammatory …

Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon

DG Couch, C Tasker, E Theophilidou, JN Lund… - Clinical …, 2017 - portlandpress.com
Objective: We sought to quantify the anti-inflammatory effects of two cannabinoid drugs,
cannabidiol (CBD) and palmitoylethanolamide (PEA), in cultured cell lines and compared …

Cannabinoids and inflammations of the gut-lung-skin barrier

C Scheau, C Caruntu, IA Badarau, AE Scheau… - Journal of Personalized …, 2021 - mdpi.com
Recent studies have identified great similarities and interferences between the epithelial
layers of the digestive tract, the airways and the cutaneous layer. The relationship between …

An Overview of Cannabidiol as a Multifunctional Drug: Pharmacokinetics and Cellular Effects

N Martinez Naya, J Kelly, G Corna, M Golino… - Molecules, 2024 - mdpi.com
Cannabidiol (CBD), a non-psychoactive compound derived from Cannabis Sativa, has
garnered increasing attention for its diverse therapeutic potential. This comprehensive …

The use of cannabinoids in colitis: a systematic review and meta-analysis

DG Couch, H Maudslay, B Doleman… - Inflammatory bowel …, 2018 - academic.oup.com
Background Clinical trials investigating the use of cannabinoid drugs for the treatment of
intestinal inflammation are anticipated secondary to preclinical literature demonstrating …

Protective application of Chinese herbal compounds and formulae in intestinal inflammation in humans and animals

Y Yang, G **ao, P Cheng, J Zeng, Y Liu - Molecules, 2023 - mdpi.com
Intestinal inflammation is a chronic gastrointestinal disorder with uncertain pathophysiology
and causation that has significantly impacted both the physical and mental health of both …