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[HTML][HTML] Multimodal experimental studies of the passive mechanical behavior of human aortas: Current approaches and future directions
Cardiovascular diseases are the leading cause of death worldwide and include, among
others, critical conditions of the aortic wall. Importantly, such critical conditions require …
others, critical conditions of the aortic wall. Importantly, such critical conditions require …
Microstructure-based biomechanics of coronary arteries in health and disease
H Chen, GS Kassab - Journal of biomechanics, 2016 - Elsevier
Coronary atherosclerosis is the major cause of mortality and disability in developed nations.
A deeper understanding of mechanical properties of coronary arteries and hence their …
A deeper understanding of mechanical properties of coronary arteries and hence their …
Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion
KM Stearns‐Reider, A D'Amore, K Beezhold… - Aging cell, 2017 - Wiley Online Library
Age‐related declines in skeletal muscle regeneration have been attributed to muscle stem
cell (MuSC) dysfunction. Aged MuSCs display a fibrogenic conversion, leading to fibrosis …
cell (MuSC) dysfunction. Aged MuSCs display a fibrogenic conversion, leading to fibrosis …
Microstructural and mechanical characterization of the layers of human descending thoracic aortas
The mechanical properties of human aortas are linked to the layered tissue and its
microstructure at different length scales. Each layer has specific mechanical and structural …
microstructure at different length scales. Each layer has specific mechanical and structural …
Bi-layered polyurethane–extracellular matrix cardiac patch improves ischemic ventricular wall remodeling in a rat model
As an intervention to abrogate ischemic cardiomyopathy, the concept of applying a
temporary, local patch to the surface of the recently infarcted ventricle has been explored …
temporary, local patch to the surface of the recently infarcted ventricle has been explored …
[HTML][HTML] Changes in the microstructure of the human aortic adventitia under biaxial loading investigated by multi-photon microscopy
A Pukaluk, H Wolinski, C Viertler, P Regitnig… - Acta Biomaterialia, 2023 - Elsevier
Among the three layers of the aortic wall, the media is primarily responsible for its
mechanical properties, but the adventitia prevents the aorta from overstretching and …
mechanical properties, but the adventitia prevents the aorta from overstretching and …
Role of smooth muscle activation in the static and dynamic mechanical characterization of human aortas
Experimental data and a suitable material model for human aortas with smooth muscle
activation are not available in the literature despite the need for develo** advanced grafts; …
activation are not available in the literature despite the need for develo** advanced grafts; …
Development and mechanical characterization of decellularized scaffolds for an active aortic graft
Decellularized porcine aortas are proposed as scaffolds for revolutionary active aortic grafts.
A change in the static and dynamic mechanical properties, associated with the …
A change in the static and dynamic mechanical properties, associated with the …
Differences in collagen fiber diameter and waviness between healthy and aneurysmal abdominal aortas
Collagen plays a key role in the strength of aortic walls, so studying micro-structural changes
during disease development is critical to better understand collagen reorganization. Second …
during disease development is critical to better understand collagen reorganization. Second …
A comprehensive study of layer-specific morphological changes in the microstructure of carotid arteries under uniaxial load
The load bearing properties of large blood vessels are principally conferred by collagen and
elastin networks and their microstructural organization plays an important role in the …
elastin networks and their microstructural organization plays an important role in the …