Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

Introduction OXA-48 and NDM are amongst the most prevalent carbapenemase types
associated with Klebsiella pneumoniae worldwide, with an increase in their prevalence in …

Scope These ESCMID guidelines address the targeted antibiotic treatment of third-
generation cephalosporin-resistant Enterobacterales (3GCephRE) and carbapenem …

Multidrug resistant Enterobacterales have become a serious global health problem, with
extended hospital stay and increased mortality. Antibiotic monotherapy has been reported …

Simple Summary Carbapenems and colistin are reserved as the last-resort treatments of
multidrug-resistant (MDR) infections in humans. Consequently, the emergence of …

Objectives: This study reports the antimicrobial activity of ceftazidime/avibactam (CZA) and
comparators against carbapenemase-producing Enterobacterales (N= 1992) and …

This study aimed to characterize the epidemiology and clinical outcomes of patients with
bloodstream infections (BSIs) due to carbapenem-resistant Klebsiella pneumoniae (CRKP) …

With the wide spread of multidrug-resistant bacteria, a variety of aminoglycosides have been
used in clinical practice as one of the effective options for antimicrobial combinations …

Background Hospital infections such as ventilator-associated pneumonia (VAP) due to
multidrug-resistant Klebsiella pneumoniae (MDR-KP) strains have increased worldwide. In …

Objectives: To determine the clinical features, outcomes, and factors associated with the
emergence of colistin-resistant gram-negative rods isolated from patients admitted to …