The scientific community worldwide has realized that malaria elimination will not be possible
without development of safe and effective transmission-blocking interventions. Primaquine …

The proportion of Plasmodium spp. infections carrying gametocytes, and gametocyte
densities, are often reported as surrogate markers for transmission potential. It remains …

Malaria transmission is dependent on the formation of gametocytes in the human blood. The
sexual conversion rate, the proportion of asexual parasites that convert into gametocytes at …

Background Cross-border malaria transmission is an important problem for national malaria
control programmes. The epidemiology of cross-border malaria is further complicated in …

Improved methods for malaria diagnosis are urgently needed. Here, we evaluate a novel
method named rotating-crystal magneto-optical detection (RMOD) in 956 suspected malaria …

Background Artemisinins (ART) are the key component of the frontline antimalarial
treatment, but their impact on Plasmodium falciparum sexual conversion rates in natural …

Background Plasmodium falciparum gametocytes are vital to sustaining malaria
transmission. Parasite densities, multiplicity of infection as well as asexual genotype are …

Presence of mature gametocyte forms of malaria parasites in peripheral blood is a key
requirement for malaria transmission. Yet, studies conducted in most malaria transmission …

Clinical studies have shown that adding a single 0.25 mg base/kg dose of primaquine to
standard antimalarial regimens rapidly sterilizes Plasmodium falciparum gametocytes …

Gametocytes are sexual stage malaria parasites responsible for transmission to mosquitoes.
Multiple gametocyte-producing clones may be present in natural infections, but the …