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[HTML][HTML] Nanosuspensions technology as a master key for nature products drug delivery and in vivo fate
Y Ma, Z Cong, P Gao, Y Wang - European Journal of Pharmaceutical …, 2023 - Elsevier
The drug nanosuspensions is a universal formulation approach for improved drug delivery
of hydrophobic drugs and one the most promising approaches for increasing the …
of hydrophobic drugs and one the most promising approaches for increasing the …
[HTML][HTML] Application of flash nanoprecipitation to fabricate poorly water-soluble drug nanoparticles
Nanoparticles are considered to be a powerful approach for the delivery of poorly water-
soluble drugs. One of the main challenges is develo** an appropriate method for …
soluble drugs. One of the main challenges is develo** an appropriate method for …
Curcumin nanoparticles inhibiting ferroptosis for the enhanced treatment of intracerebral hemorrhage
C Yang, M Han, R Li, L Zhou, Y Zhang… - International journal …, 2021 - Taylor & Francis
Background Intracerebral hemorrhage (ICH) is a form of severe stroke, the pathology of
which is tied closely to a recently discovered form of programmed cell death known as …
which is tied closely to a recently discovered form of programmed cell death known as …
Drug nanocrystals: Fabrication methods and promising therapeutic applications
The drug nanocrystals (NCs) with unique physicochemical properties are now considered
as a promising drug delivery system for poorly water-soluble drugs. So far> 20 formulations …
as a promising drug delivery system for poorly water-soluble drugs. So far> 20 formulations …
Enhanced topical penetration, system exposure and anti-psoriasis activity of two particle-sized, curcumin-loaded PLGA nanoparticles in hydrogel
Psoriasis is an immune-mediated skin disorder, which is triggered by the aberrant activation
of dendritic cells in skin. This activation is followed by the complex interaction between the …
of dendritic cells in skin. This activation is followed by the complex interaction between the …
Recent advances in natural small molecules as drug delivery systems
S Fu, X Yang - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Drug delivery systems (DDSs) are a multidisciplinary approach toward the effective delivery
of drugs to their target sites. Natural small molecule (NSM) compounds with anticancer …
of drugs to their target sites. Natural small molecule (NSM) compounds with anticancer …
Nanoformulations of ursolic acid: A modern natural anticancer molecule
L Wang, Q Yin, C Liu, Y Tang, C Sun… - Frontiers in …, 2021 - frontiersin.org
Background: Ursolic acid (UA) is a natural pentacyclic triterpene derived from fruit, herb, and
other plants. UA can act on molecular targets of various signaling pathways, inhibit the …
other plants. UA can act on molecular targets of various signaling pathways, inhibit the …
Safety of nanosuspensions in drug delivery
L Wang, J Du, Y Zhou, Y Wang - Nanomedicine: Nanotechnology, Biology …, 2017 - Elsevier
Nanosuspension technology is currently undergoing dramatic expansion in pharmaceutical
science research and development. However, most of the research efforts generally focus …
science research and development. However, most of the research efforts generally focus …
[HTML][HTML] Evolution from small molecule to nano-drug delivery systems: An emerging approach for cancer therapy of ursolic acid
J Shao, Y Fang, R Zhao, F Chen, M Yang… - Asian Journal of …, 2020 - Elsevier
Ursolic acid (UA), a natural pentacyclic triterpenoid, possesses widespread biological and
pharmacological activities. However, drawbacks such as low bioavailability, poor targeting …
pharmacological activities. However, drawbacks such as low bioavailability, poor targeting …
Small-sized mPEG–PLGA nanoparticles of Schisantherin A with sustained release for enhanced brain uptake and anti-parkinsonian activity
Schisantherin A (SA) is a promising anti-Parkinsonism natural product. However, its poor
water solubility and rapid serum clearance impose significant barriers to delivery of SA to the …
water solubility and rapid serum clearance impose significant barriers to delivery of SA to the …