[HTML][HTML] Nanosuspensions technology as a master key for nature products drug delivery and in vivo fate

Y Ma, Z Cong, P Gao, Y Wang - European Journal of Pharmaceutical …, 2023 - Elsevier
The drug nanosuspensions is a universal formulation approach for improved drug delivery
of hydrophobic drugs and one the most promising approaches for increasing the …

[HTML][HTML] Application of flash nanoprecipitation to fabricate poorly water-soluble drug nanoparticles

J Tao, SF Chow, Y Zheng - Acta pharmaceutica sinica B, 2019 - Elsevier
Nanoparticles are considered to be a powerful approach for the delivery of poorly water-
soluble drugs. One of the main challenges is develo** an appropriate method for …

Curcumin nanoparticles inhibiting ferroptosis for the enhanced treatment of intracerebral hemorrhage

C Yang, M Han, R Li, L Zhou, Y Zhang… - International journal …, 2021 - Taylor & Francis
Background Intracerebral hemorrhage (ICH) is a form of severe stroke, the pathology of
which is tied closely to a recently discovered form of programmed cell death known as …

Drug nanocrystals: Fabrication methods and promising therapeutic applications

IS Mohammad, H Hu, L Yin, W He - International journal of pharmaceutics, 2019 - Elsevier
The drug nanocrystals (NCs) with unique physicochemical properties are now considered
as a promising drug delivery system for poorly water-soluble drugs. So far> 20 formulations …

Enhanced topical penetration, system exposure and anti-psoriasis activity of two particle-sized, curcumin-loaded PLGA nanoparticles in hydrogel

L Sun, Z Liu, L Wang, D Cun, HHY Tong, R Yan… - Journal of Controlled …, 2017 - Elsevier
Psoriasis is an immune-mediated skin disorder, which is triggered by the aberrant activation
of dendritic cells in skin. This activation is followed by the complex interaction between the …

Recent advances in natural small molecules as drug delivery systems

S Fu, X Yang - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Drug delivery systems (DDSs) are a multidisciplinary approach toward the effective delivery
of drugs to their target sites. Natural small molecule (NSM) compounds with anticancer …

Nanoformulations of ursolic acid: A modern natural anticancer molecule

L Wang, Q Yin, C Liu, Y Tang, C Sun… - Frontiers in …, 2021 - frontiersin.org
Background: Ursolic acid (UA) is a natural pentacyclic triterpene derived from fruit, herb, and
other plants. UA can act on molecular targets of various signaling pathways, inhibit the …

Safety of nanosuspensions in drug delivery

L Wang, J Du, Y Zhou, Y Wang - Nanomedicine: Nanotechnology, Biology …, 2017 - Elsevier
Nanosuspension technology is currently undergoing dramatic expansion in pharmaceutical
science research and development. However, most of the research efforts generally focus …

[HTML][HTML] Evolution from small molecule to nano-drug delivery systems: An emerging approach for cancer therapy of ursolic acid

J Shao, Y Fang, R Zhao, F Chen, M Yang… - Asian Journal of …, 2020 - Elsevier
Ursolic acid (UA), a natural pentacyclic triterpenoid, possesses widespread biological and
pharmacological activities. However, drawbacks such as low bioavailability, poor targeting …

Small-sized mPEG–PLGA nanoparticles of Schisantherin A with sustained release for enhanced brain uptake and anti-parkinsonian activity

T Chen, C Li, Y Li, X Yi, R Wang… - ACS applied materials …, 2017 - ACS Publications
Schisantherin A (SA) is a promising anti-Parkinsonism natural product. However, its poor
water solubility and rapid serum clearance impose significant barriers to delivery of SA to the …