An update on the effects of vitamin D on the immune system and autoimmune diseases

C Sîrbe, S Rednic, A Grama, TL Pop - International journal of molecular …, 2022 - mdpi.com
Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …

Immunology of Mycobacterium tuberculosis Infections

JK Sia, J Rengarajan - Microbiology spectrum, 2019 - Am Soc Microbiol
Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …

[HTML][HTML] Vitamin D and chronic diseases

H Wang, W Chen, D Li, X Yin, X Zhang, N Olsen… - Aging and …, 2017 - ncbi.nlm.nih.gov
Vitamin D is one of the essential nutrients to sustain the human health. As a member of the
steroid hormone family, it has a classic role in regulating metabolism of calcium and a non …

Macrophage defense mechanisms against intracellular bacteria

G Weiss, UE Schaible - Immunological reviews, 2015 - Wiley Online Library
Macrophages and neutrophils play a decisive role in host responses to intracellular bacteria
including the agent of tuberculosis (TB), M ycobacterium tuberculosis as they represent the …

Immune system dysregulation during spaceflight: potential countermeasures for deep space exploration missions

BE Crucian, A Choukèr, RJ Simpson, S Mehta… - Frontiers in …, 2018 - frontiersin.org
Recent studies have established that dysregulation of the human immune system and the
reactivation of latent herpesviruses persists for the duration of a 6-month orbital spaceflight …

US Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of non-tuberculous mycobacteria in …

RA Floto, KN Olivier, L Saiman, CL Daley, JL Herrmann… - Thorax, 2016 - thorax.bmj.com
Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that can
cause chronic pulmonary infection, particularly in individuals with pre-existing inflammatory …

[HTML][HTML] Inflammation-mediated tissue damage in pulmonary tuberculosis and host-directed therapeutic strategies

D Tiwari, AR Martineau - Seminars in Immunology, 2023 - Elsevier
Abstract Treatment of tuberculosis (TB) involves the administration of anti-mycobacterial
drugs for several months. The emergence of drug-resistant strains of Mycobacterium …

Vitamin D-mediated hypercalcemia: mechanisms, diagnosis, and treatment

PJ Tebben, RJ Singh, R Kumar - Endocrine reviews, 2016 - academic.oup.com
Hypercalcemia occurs in up to 4% of the population in association with malignancy, primary
hyperparathyroidism, ingestion of excessive calcium and/or vitamin D, ectopic production of …

Impact of childhood malnutrition on host defense and infection

MK Ibrahim, M Zambruni, CL Melby… - Clinical microbiology …, 2017 - Am Soc Microbiol
The global impact of childhood malnutrition is staggering. The synergism between
malnutrition and infection contributes substantially to childhood morbidity and mortality …

The immune response in tuberculosis

A O'Garra, PS Redford, FW McNab… - Annual review of …, 2013 - annualreviews.org
There are 9 million cases of active tuberculosis reported annually; however, an estimated
one-third of the world's population is infected with Mycobacterium tuberculosis and remains …