Transposable elements shape the evolution of mammalian development
AD Senft, TS Macfarlan - Nature Reviews Genetics, 2021 - nature.com
Transposable elements (TEs) promote genetic innovation but also threaten genome stability.
Despite multiple layers of host defence, TEs actively shape mammalian-specific …
Despite multiple layers of host defence, TEs actively shape mammalian-specific …
Vertebrate endoderm development and organ formation
The endoderm germ layer contributes to the respiratory and gastrointestinal tracts and to all
of their associated organs. Over the past decade, studies in vertebrate model organisms …
of their associated organs. Over the past decade, studies in vertebrate model organisms …
The role of KRAB-ZFPs in transposable element repression and mammalian evolution
Kruppel-associated box zinc-finger proteins (KRAB-ZFPs) make up the largest family of
transcription factors in humans. These proteins emerged in the last common ancestor of …
transcription factors in humans. These proteins emerged in the last common ancestor of …
An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure
MJ Harris, DM Juriloff - Birth Defects Research Part A: Clinical …, 2010 - Wiley Online Library
The number of mouse mutants and strains with neural tube defects (NTDs) now exceeds
240, including 205 representing specific genes, 30 for unidentified genes, and 9 …
240, including 205 representing specific genes, 30 for unidentified genes, and 9 …
The arms race between KRAB–zinc finger proteins and endogenous retroelements and its impact on mammals
M Bruno, M Mahgoub… - Annual Review of …, 2019 - annualreviews.org
Nearly half of the human genome consists of endogenous retroelements (EREs) and their
genetic remnants, a small fraction of which carry the potential to propagate in the host …
genetic remnants, a small fraction of which carry the potential to propagate in the host …
Adaptive evolution in zinc finger transcription factors
RO Emerson, JH Thomas - PLoS genetics, 2009 - journals.plos.org
The majority of human genes are conserved among mammals, but some gene families have
undergone extensive expansion in particular lineages. Here, we present an evolutionary …
undergone extensive expansion in particular lineages. Here, we present an evolutionary …
Vertebrate intestinal endoderm development
The endoderm gives rise to the lining of the esophagus, stomach and intestines, as well as
associated organs. To generate a functional intestine, a series of highly orchestrated …
associated organs. To generate a functional intestine, a series of highly orchestrated …
Coevolution of retroelements and tandem zinc finger genes
JH Thomas, S Schneider - Genome research, 2011 - genome.cshlp.org
Vertebrate genomes encode large and highly variable numbers of tandem C2H2 zinc finger
(tandem ZF) transcription factor proteins. In mammals, most tandem ZF genes also encode a …
(tandem ZF) transcription factor proteins. In mammals, most tandem ZF genes also encode a …
The genomic architecture of segmental duplications and associated copy number variants in dogs
Structural variation is an important and abundant source of genetic and phenotypic variation.
Here we describe the first systematic and genome-wide analysis of segmental duplications …
Here we describe the first systematic and genome-wide analysis of segmental duplications …
A common mode of recognition for methylated CpG
Much is known about vertebrate DNA methylation, however it is not known how methylated
CpG within particular sequences is recognized. Two recent structures of C2H2 zinc finger …
CpG within particular sequences is recognized. Two recent structures of C2H2 zinc finger …