De novo drug development is an expensive and time-consuming process. It is known that
the total average development cost for a new drug ranges from $2 to $3 billion and the total …

Computational drug repositioning or repurposing is a promising and efficient tool for
discovering new uses from existing drugs and holds the great potential for precision …

Experimental drug development is time-consuming, expensive and limited to a relatively
small number of targets. However, recent studies show that repositioning of existing drugs …

The strategy of using existing drugs originally developed for one disease to treat other
indications has found success across medical fields. Such drug repurposing promises faster …

Traditionally, drug discovery utilises a de novo design approach, which requires high cost
and many years of drug development before it reaches the market. Novel drug development …

Due to the huge amount of biological and medical data available today, along with well-
established machine learning algorithms, the design of largely automated drug development …

Highlights•A bibliometric review of drug repurposing provides novel insights into the
practice.•Some drugs have been tried in hundreds of diseases.•Even an old drug like …

Background In the era of information overload, natural language processing (NLP)
techniques are increasingly needed to support advanced biomedical information …

The recent years have witnessed a rapid increase in the number of scientific articles in
biomedical domain. These literature are mostly available and readily accessible in …

Since its introduction in the late nineteen eighties, the discipline of Enterprise Architecture
(EA) has evolved into a well-known practice of managing information systems in alignment …