The increasing life expectancy has led to a higher incidence of age-related
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …

Inflammation is an essential immune response that helps fight infections and heal tissues.
However, chronic inflammation has been linked to several diseases, including cancer …

Rationale: Pyroptosis is a morphologically and mechanistically distinct form of cell death and
is characterized by GSDMD (gasdermin D) or GSDME (gasdermin E)-mediated necrosis …

More than a decade has passed since the conceptualization of the “alarmin” hypothesis. The
alarmin family has been expanding in terms of both number and the concept. It has recently …

Inflammation occurs as a result of exposure of tissues and organs to harmful stimuli such as
microbial pathogens, irritants, or toxic cellular components. The primary physical …

High blood pressure is present in more than one billion adults worldwide and is the most
important modifiable risk factor of death resulting from cardiovascular disease. While many …

Neuroinflammation has been identified as a causative factor of multiple neurological
diseases. The nucleotide-binding oligomerization domain-, leucine-rich repeat-and pyrin …

Interleukin (IL)-33 belongs to IL-1 cytokine family which is constitutively produced from the
structural and lining cells including fibroblasts, endothelial cells, and epithelial cells of skin …

INTRODUCTION The inflammasomes and the complement system are traditionally viewed
as quintessential components of innate immunity required for the detection and elimination …

Background The effectual immune response is crucial to defeat viral infections. However,
exuberant immune response with features of macrophage activation syndrome (MAS) lead …