Subcellular targeting strategies for drug design and delivery
Many drug targets are localized to particular subcellular compartments, yet current drug
design strategies are focused on bioavailability and tissue targeting and rarely address drug …
design strategies are focused on bioavailability and tissue targeting and rarely address drug …
Physiology of the prion protein
Prion diseases are transmissible spongiform encephalopathies (TSEs), attributed to
conformational conversion of the cellular prion protein (PrPC) into an abnormal conformer …
conformational conversion of the cellular prion protein (PrPC) into an abnormal conformer …
Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion
P Srinivasan, WL Beatty, A Diouf… - Proceedings of the …, 2011 - National Acad Sciences
The commitment of Plasmodium merozoites to invade red blood cells (RBCs) is marked by
the formation of a junction between the merozoite and the RBC and the coordinated …
the formation of a junction between the merozoite and the RBC and the coordinated …
[HTML][HTML] Flavonoid–membrane interactions: Involvement of flavonoid–metal complexes in raft signaling
YS Tarahovsky, YA Kim, EA Yagolnik… - Biochimica et Biophysica …, 2014 - Elsevier
Flavonoids are polyphenolic compounds produced by plants and delivered to the human
body through food. Although the epidemiological analyses of large human populations did …
body through food. Although the epidemiological analyses of large human populations did …
Malaria and human red blood cells
Invasion by the malaria parasite, Plasmodium falciparum, brings about extensive changes in
the host red cells. These include loss of the normal discoid shape, increased rigidity of the …
the host red cells. These include loss of the normal discoid shape, increased rigidity of the …
An overview about erythrocyte membrane
S De Oliveira, C Saldanha - Clinical hemorheology and …, 2010 - content.iospress.com
An overview about erythrocyte membrane Page 1 Clinical Hemorheology and
Microcirculation 44 (2010) 63–74 63 DOI 10.3233/CH-2010-1253 IOS Press An overview …
Microcirculation 44 (2010) 63–74 63 DOI 10.3233/CH-2010-1253 IOS Press An overview …
Lipids in host–pathogen interactions: pathogens exploit the complexity of the host cell lipidome
YPM van der Meer-Janssen, J van Galen… - Progress in lipid …, 2010 - Elsevier
Lipids were long believed to have a structural role in biomembranes and a role in energy
storage utilizing cellular lipid droplets and plasma lipoproteins. Research over the last …
storage utilizing cellular lipid droplets and plasma lipoproteins. Research over the last …
Hardly vacuous: The parasitophorous vacuolar membrane of malaria parasites
When a malaria parasite invades a host erythrocyte it pushes itself in and invaginates a
portion of the host membrane, thereby sealing itself inside and establishing itself in the …
portion of the host membrane, thereby sealing itself inside and establishing itself in the …
Rafts making and rafts braking: how plant flavonoids may control membrane heterogeneity
YS Tarahovsky, EN Muzafarov, YA Kim - Molecular and cellular …, 2008 - Springer
Plant flavonoids are not only known as powerful antioxidants, but also as cell metabolism
regulators. It has been postulated that they are able to control cell signal pathways by …
regulators. It has been postulated that they are able to control cell signal pathways by …
Erythrocyte remodeling by malaria parasites
K Haldar, N Mohandas - Current opinion in hematology, 2007 - journals.lww.com
Erythrocyte remodeling by malaria parasites : Current Opinion in Hematology Erythrocyte
remodeling by malaria parasites : Current Opinion in Hematology Log in or Register Subscribe to …
remodeling by malaria parasites : Current Opinion in Hematology Log in or Register Subscribe to …