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Alzheimer's disease: an updated overview of its genetics
Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. It is
classified as familial and sporadic. The dominant familial or autosomal presentation …
classified as familial and sporadic. The dominant familial or autosomal presentation …
Neuroinflammation as a common feature of neurodegenerative disorders
Neurodegenerative diseases share the fact that they derive from altered proteins that
undergo an unfolding process followed by formation of β-structures and a pathological …
undergo an unfolding process followed by formation of β-structures and a pathological …
Insulin resistance and oxidative stress in the brain: what's new?
The latest studies have indicated a strong relationship between systemic insulin resistance
(IR) and higher incidence of neurodegeneration, dementia, and mild cognitive impairment …
(IR) and higher incidence of neurodegeneration, dementia, and mild cognitive impairment …
Neuroinflammation in the pathogenesis of Alzheimer's disease. A rational framework for the search of novel therapeutic approaches
I Morales, L Guzmán-Martínez… - Frontiers in cellular …, 2014 - frontiersin.org
Alzheimer disease (AD) is the most common cause of dementia in people over 60 years old.
The molecular and cellular alterations that trigger this disease are still diffuse, one of the …
The molecular and cellular alterations that trigger this disease are still diffuse, one of the …
Neuroimmune connections in aging and neurodegenerative diseases
In recent years, the inter-relationship between the innate immune system and the central
nervous system (CNS) has moved to the forefront of biomedical research, with the discovery …
nervous system (CNS) has moved to the forefront of biomedical research, with the discovery …
Genetic and environmental factors in Alzheimer's and Parkinson's diseases and promising therapeutic intervention via fecal microbiota transplantation
H Wang, F Yang, S Zhang, R **n, Y Sun - npj Parkinson's Disease, 2021 - nature.com
Neurodegenerative diseases are characterized by neuronal impairment and loss of function,
and with the major shared histopathological hallmarks of misfolding and aggregation of …
and with the major shared histopathological hallmarks of misfolding and aggregation of …
Brain metabolic dysfunction at the core of Alzheimer's disease
Growing evidence supports the concept that Alzheimer's disease (AD) is fundamentally a
metabolic disease with molecular and biochemical features that correspond with diabetes …
metabolic disease with molecular and biochemical features that correspond with diabetes …
Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease
S M. de la Monte - Current Alzheimer Research, 2012 - benthamdirect.com
Alzheimer's disease [AD] is the most common cause of dementia in North America. Despite
30+ years of intense investigation, the field lacks consensus regarding the etiology and …
30+ years of intense investigation, the field lacks consensus regarding the etiology and …
Is psychosis a multisystem disorder? A meta-review of central nervous system, immune, cardiometabolic, and endocrine alterations in first-episode psychosis and …
People with psychotic disorders show abnormalities in several organ systems in addition to
the central nervous system (CNS); and this contributes to excess mortality. However, it is …
the central nervous system (CNS); and this contributes to excess mortality. However, it is …
Different brain regions are infected with fungi in Alzheimer's disease
The possibility that Alzheimer's disease (AD) has a microbial aetiology has been proposed
by several researchers. Here, we provide evidence that tissue from the central nervous …
by several researchers. Here, we provide evidence that tissue from the central nervous …