Understanding of ROS‐inducing strategy in anticancer therapy
SJ Kim, HS Kim, YR Seo - Oxidative medicine and cellular …, 2019 - Wiley Online Library
Redox homeostasis is essential for the maintenance of diverse cellular processes. Cancer
cells have higher levels of reactive oxygen species (ROS) than normal cells as a result of …
cells have higher levels of reactive oxygen species (ROS) than normal cells as a result of …
Drug resistance in glioblastoma: the two faces of oxidative stress
Glioblastomas (GBM) are the most common primary brain tumor with a median survival of 15
months. A population of cells with stem cell properties (glioblastoma stem cells, GSCs) …
months. A population of cells with stem cell properties (glioblastoma stem cells, GSCs) …
Cancer cells co-opt the neuronal redox-sensing channel TRPA1 to promote oxidative-stress tolerance
Cancer cell survival is dependent on oxidative-stress defenses against reactive oxygen
species (ROS) that accumulate during tumorigenesis. Here, we show a non-canonical …
species (ROS) that accumulate during tumorigenesis. Here, we show a non-canonical …
Molecular and cellular paradigms of multidrug resistance in cancer
Background The acquisition of resistance to chemotherapy is a major hurdle in the
successful application of cancer therapy. Several anticancer approaches, including …
successful application of cancer therapy. Several anticancer approaches, including …
Radiation resistance: a matter of transcription factors
C Galeaz, C Totis, A Bisio - Frontiers in oncology, 2021 - frontiersin.org
Currently, radiation therapy is one of the standard therapies for cancer treatment. Since the
first applications, the field of radiotherapy has constantly improved, both in imaging …
first applications, the field of radiotherapy has constantly improved, both in imaging …
Long non-coding RNAs (lncRNAs) signaling in cancer chemoresistance: from prediction to druggability
GC Eptaminitaki, D Stellas, B Bonavida… - Drug Resistance Updates, 2022 - Elsevier
The acquisition of cancer cell resistance to conventional chemotherapeutics is considered
the major driver of treatment failure and disease recurrence in most solid and hematological …
the major driver of treatment failure and disease recurrence in most solid and hematological …
Apigenin as tumor suppressor in cancers: Biotherapeutic activity, nanodelivery, and mechanisms with emphasis on pancreatic cancer
Pancreatic cancer is the most lethal malignancy of the gastrointestinal tract. Due to its
propensity for early local and distant spread, affected patients possess extremely poor …
propensity for early local and distant spread, affected patients possess extremely poor …
[HTML][HTML] Regulation of multidrug resistance by microRNAs in anti-cancer therapy
X An, C Sarmiento, T Tan, H Zhu - Acta Pharmaceutica Sinica B, 2017 - Elsevier
Multidrug resistance (MDR) remains a major clinical obstacle to successful cancer treatment.
Although diverse mechanisms of MDR have been well elucidated, such as dysregulation of …
Although diverse mechanisms of MDR have been well elucidated, such as dysregulation of …
Redox regulation in tumor cell epithelial–mesenchymal transition: Molecular basis and therapeutic strategy
Epithelial–mesenchymal transition (EMT) is recognized as a driving force of cancer cell
metastasis and drug resistance, two leading causes of cancer recurrence and cancer …
metastasis and drug resistance, two leading causes of cancer recurrence and cancer …
[HTML][HTML] ent-Kaurane diterpenoids induce apoptosis and ferroptosis through targeting redox resetting to overcome cisplatin resistance
Y Sun, Y Qiao, Y Liu, J Zhou, X Wang, H Zheng, Z Xu… - Redox biology, 2021 - Elsevier
Reactive oxygen species (ROS) induction is an effective mechanism to kill cancer cells for
many chemotherapeutics, while resettled redox homeostasis induced by the anticancer …
many chemotherapeutics, while resettled redox homeostasis induced by the anticancer …