Molecular engineering of glycosaminoglycan chemistry for biomolecule delivery
Glycosaminoglycans (GAGs) are linear, negatively charged polysaccharides that interact
with a variety of positively charged growth factors. In this review article the effects of …
with a variety of positively charged growth factors. In this review article the effects of …
Galactosaminoglycans: medical applications and drawbacks
VH Pomin, WP Vignovich, AV Gonzales… - Molecules, 2019 - mdpi.com
Galactosaminoglycans (GalAGs) are sulfated glycans composed of alternating N-
acetylgalactosamine and uronic acid units. Uronic acid epimerization, sulfation patterns and …
acetylgalactosamine and uronic acid units. Uronic acid epimerization, sulfation patterns and …
Consensus on the rational use of antithrombotics in veterinary critical care (CURATIVE): domain 4—refining and monitoring antithrombotic therapies
CR Sharp, AM deLaforcade… - Journal of veterinary …, 2019 - Wiley Online Library
Objectives To systematically review the evidence for therapeutic monitoring of antithrombotic
drugs in small animals, develop guidelines regarding antithrombotic monitoring, and identify …
drugs in small animals, develop guidelines regarding antithrombotic monitoring, and identify …
[HTML][HTML] Dermatan sulfate is the predominant antithrombotic glycosaminoglycan in vessel walls: implications for a possible physiological function of heparin cofactor II
AMF Tovar, DA de Mattos, MP Stelling… - … et Biophysica Acta (BBA …, 2005 - Elsevier
The role of different glycosaminoglycan species from the vessel walls as physiological
antithrombotic agents remains controversial. To further investigate this aspect we extracted …
antithrombotic agents remains controversial. To further investigate this aspect we extracted …
High plasma heparin cofactor II activity is associated with reduced incidence of in-stent restenosis after percutaneous coronary intervention
N Takamori, H Azuma, M Kato, S Hashizume… - Circulation, 2004 - Am Heart Assoc
Background—Thrombin plays an important role in the development of atherosclerosis and
restenosis after percutaneous coronary intervention. Because heparin cofactor II (HCII) …
restenosis after percutaneous coronary intervention. Because heparin cofactor II (HCII) …
Utility and control of proteoglycans in tissue engineering
This review addresses various methods of integrating proteoglycans (PGs) into the design of
engineered tissues and provides insight for designing tissue-engineered disease models …
engineered tissues and provides insight for designing tissue-engineered disease models …
Pharmacologic inhibition of platelet vWF-GPIbα interaction prevents coronary artery thrombosis
JK Hennan, RE Swillo, GA Morgan… - Thrombosis and …, 2006 - thieme-connect.com
Under high shear arterial blood flow von Willebrand Factor (vWF) binds the platelet receptor
glycoprotein (GP) Ibα, leading to platelet adhesion, activation and thrombosis. Blockade of …
glycoprotein (GP) Ibα, leading to platelet adhesion, activation and thrombosis. Blockade of …
Structural composition and anticoagulant activity of dermatan sulfate from the skin of the electric eel, Electrophorus electricus (L.)
MLS Souza, JMM Dellias, FR Melo, LCF Silva - … and Physiology Part B …, 2007 - Elsevier
We determined the disaccharide composition of dermatan sulfate (DS) purified from the skin
of the electric eel Electrophorus electricus. DS obtained from the electric eel was composed …
of the electric eel Electrophorus electricus. DS obtained from the electric eel was composed …
Antithrombotic and anticomplementary properties of a very low molecular mass dermatan sulfate
MF Alberto, DG Romero, M Lazzari, GC Calabrese - Thrombosis research, 2008 - Elsevier
INTRODUCTION: Dermatan sulfate, a sulfated glycosaminoglycan, acts as an anticoagulant
by accelerating the inhibition of thrombin by heparin cofactor II. MATERIALS AND …
by accelerating the inhibition of thrombin by heparin cofactor II. MATERIALS AND …