Plants respond to environmental pollutants such as heavy metal (s) by triggering the
expression of genes that encode proteins involved in stress response. Toxic metal ions …

Each protein must be synthesized with the correct amino acid sequence, folded into its
native structure, and transported to a relevant subcellular location and protein complex. If …

Small heat shock proteins (sHsps) are a ubiquitous and ancient family of ATP-independent
molecular chaperones. A key characteristic of sHsps is that they exist in ensembles of iso …

Cells respond to protein-damaging (proteotoxic) stress by activation of the Heat Shock
Response (HSR). The HSR provides cells with an enhanced ability to endure proteotoxic …

Plants respond to various stresses by triggering the expression of genes that encode
proteins involved in plant growth, fruit ripening, cellular protein homeostasis, and tolerance …

Misfolding, aggregation, and aberrant accumulation of proteins are central components in
the progression of neurodegenerative disease. Cellular molecular chaperone systems …

In neurons, but also in all other cells the complex proteostasis network is monitored and
tightly regulated by the cellular protein quality control (PQC) system. Beyond folding of newly …

The chronic infections by pathogenic Pseudomonas aeruginosa (P. aeruginosa) remain to
be properly addressed. In particular, for drug‐resistant strains, limited medication is …

The protein quality control (PQC) system maintains protein homeostasis by counteracting
the accumulation of misfolded protein conformers. Substrate degradation and refolding …

Protein homeostasis (proteostasis) is an essential pillar for correct cellular function.
Impairments in proteostasis are encountered both in aging and in several human disease …