Recent advances in nanomaterial-based synergistic combination cancer immunotherapy

W Sang, Z Zhang, Y Dai, X Chen - Chemical Society Reviews, 2019 - pubs.rsc.org
In recent years, conventional treatments including surgery, chemotherapy and radiotherapy
have been the main approaches in tumour therapy. Cancer immunotherapy is a new …

[HTML][HTML] Polysaccharide-based nanomedicines for cancer immunotherapy: A review

Y Zeng, Y **ang, R Sheng, H Tomás, J Rodrigues… - Bioactive Materials, 2021 - Elsevier
Cancer immunotherapy is an effective antitumor approach through activating immune
systems to eradicate tumors by immunotherapeutics. However, direct administration of …

Click-reaction-mediated chemotherapy and photothermal therapy synergistically inhibit breast cancer in mice

G Zhang, X Chen, X Chen, K Du, K Ding, D He… - ACS …, 2023 - ACS Publications
The development of functional materials for tumor immunogenicity enhancement is
desirable for overcoming the low therapeutic efficiency and easy metastasis during tumor …

mRNA-based cancer vaccines: a therapeutic strategy for the treatment of melanoma patients

M Bidram, Y Zhao, NG Shebardina, AV Baldin… - Vaccines, 2021 - mdpi.com
Malignant melanoma is one of the most aggressive forms of cancer and the leading cause of
death from skin tumors. Given the increased incidence of melanoma diagnoses in recent …

TCR redirected T cells for cancer treatment: achievements, hurdles, and goals

F Manfredi, BC Cianciotti, A Potenza, E Tassi… - Frontiers in …, 2020 - frontiersin.org
Adoptive T cell therapy (ACT) is a rapidly evolving therapeutic approach designed to
harness T cell specificity and function to fight diseases. Based on the evidence that T …

Immune checkpoint inhibitors in cancer therapy—how to overcome drug resistance?

Y Lao, D Shen, W Zhang, R He, M Jiang - Cancers, 2022 - mdpi.com
Simple Summary Immune checkpoint inhibitors (ICIs) are an important strategy in cancer
therapy. However, with the widespread clinical use of ICIs, people gradually found that ICIs …

Metal-based nano-vaccines for cancer immunotherapy

J Li, H Ren, Y Zhang - Coordination Chemistry Reviews, 2022 - Elsevier
Cancer vaccination is an effective way to prevent or cure cancers by inducing strong cellular
and humoral immunity with the aid of delivery carriers or adjuvants. Increasing new delivery …

Evolution and progress of mRNA vaccines in the treatment of melanoma: future prospects

D Bafaloukos, I Gazouli, C Koutserimpas, G Samonis - Vaccines, 2023 - mdpi.com
mRNA vaccines encoding tumor antigens may be able to sensitize the immune system of the
host against cancer cells, enhancing antigen presentation and immune response. Since the …

[HTML][HTML] Identification of three tumor antigens and immune subtypes for mRNA vaccine development in diffuse glioma

Q Zhou, X Yan, H Zhu, Z **n, J Zhao, W Shen, W Yin… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Diffuse glioma patients have high mortality and recurrence despite multimodal
therapies. This study aims to identify the potential tumor antigens for mRNA vaccines and …

Cell surface sphingomyelin: Key role in cancer initiation, progression, and immune evasion

H Tallima, HME Azzazy, R El Ridi - Lipids in Health and Disease, 2021 - Springer
Cell surface biochemical changes, notably excessive increase in outer leaflet sphingomyelin
(SM) content, are important in cancer initiation, growth, and immune evasion. Innumerable …