Progress in the Chemistry of Tetrahydroquinolines
Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, being
widespread in nature and present in a broad variety of pharmacologically active …
widespread in nature and present in a broad variety of pharmacologically active …
Oxidative cyclization in natural product biosynthesis
MC Tang, Y Zou, K Watanabe, CT Walsh… - Chemical …, 2017 - ACS Publications
Oxidative cyclizations are important transformations that occur widely during natural product
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …
Biosynthesis of fungal meroterpenoids
Covering: up to September 2015 Meroterpenoids are hybrid natural products that partially
originate from the terpenoid pathway. The meroterpenoids derived from fungi display quite …
originate from the terpenoid pathway. The meroterpenoids derived from fungi display quite …
FAD-dependent enzyme-catalysed intermolecular [4+ 2] cycloaddition in natural product biosynthesis
L Gao, C Su, X Du, R Wang, S Chen, Y Zhou, C Liu… - Nature Chemistry, 2020 - nature.com
Abstract The Diels–Alder reaction is one of the most powerful and widely used methods in
synthetic chemistry for the stereospecific construction of carbon–carbon bonds. Despite the …
synthetic chemistry for the stereospecific construction of carbon–carbon bonds. Despite the …
Biosynthesis of cyclopropane in natural products
Covering: 2012 to 2021 Cyclopropane attracts wide interests in the fields of synthetic and
pharmaceutical chemistry, and chemical biology because of its unique structural and …
pharmaceutical chemistry, and chemical biology because of its unique structural and …
Terpene synthases in disguise: enzymology, structure, and opportunities of non-canonical terpene synthases
Covering: up to July 2019 Terpene synthases (TSs) are responsible for generating much of
the structural diversity found in the superfamily of terpenoid natural products. These elegant …
the structural diversity found in the superfamily of terpenoid natural products. These elegant …
Prenyltransferases as key enzymes in primary and secondary metabolism
J Winkelblech, A Fan, SM Li - Applied microbiology and biotechnology, 2015 - Springer
Attachment of isoprene units to various acceptors by prenylation plays an important role in
primary and secondary metabolism of living organisms. Protein prenylation belongs to …
primary and secondary metabolism of living organisms. Protein prenylation belongs to …
Hunting for the Intermolecular Diels–Alderase
L Gao, Q Ding, X Lei - Accounts of Chemical Research, 2024 - ACS Publications
Conspectus The Diels–Alder reaction is well known as a concerted [4+ 2] cycloaddition
governed by the Woodward–Hoffmann rules. Since Prof. Otto Diels and his student Kurt …
governed by the Woodward–Hoffmann rules. Since Prof. Otto Diels and his student Kurt …
Biosynthesis of cosmosporasides reveals the assembly line for fungal hybrid terpenoid saccharides
GY Yuan, JM Zhang, QD Xu, HR Zhang… - Angewandte …, 2023 - Wiley Online Library
Fungal hybrid terpenoid saccharides constitute a new and growing family of natural products
with significant biomedical and agricultural activities. One representative family is the …
with significant biomedical and agricultural activities. One representative family is the …
Diaporisoindoles A–C: Three Isoprenylisoindole Alkaloid Derivatives from the Mangrove Endophytic Fungus Diaporthe sp. SYSU-HQ3
H Cui, Y Lin, M Luo, Y Lu, X Huang, Z She - Organic letters, 2017 - ACS Publications
Diaporisoindoles A (1) and B (2), two novel isoprenylisoindole alkaloids, and an unusual
diisoprenylisoindole dimer diaporisoindole C (3), together with a precursor tenellone C (4) …
diisoprenylisoindole dimer diaporisoindole C (3), together with a precursor tenellone C (4) …