Hypertensive eye disease includes a spectrum of pathological changes, the most well
known being hypertensive retinopathy. Other commonly involved parts of the eye in …

Abstract Optical Coherence Tomography (OCT) has revolutionized ophthalmology. Since its
introduction in the early 1990s it has continuously improved in terms of speed, resolution …

Retinal blood vessels provide information on the risk of cardiovascular disease (CVD). Here,
we report the development and validation of deep-learning models for the automated …

Background: The microvasculature, the smallest blood vessels in the body, has key roles in
maintenance of organ health and tumorigenesis. The retinal fundus is a window for human …

With increase in life expectancy, the number of persons suffering from common age-related
brain diseases, including neurodegenerative (eg, dementia) and cerebrovascular (eg …

Objective: Reduction in capillary density or rarefaction is a hallmark of essential
hypertension. We measured the retinal capillary density using noninvasive optical …

Background ageing is an important risk factor for a variety of human pathologies. Biological
age (BA) may better capture ageing-related physiological changes compared with …

Vascular remodeling is an important pathological feature of hypertension, leading to
increased vascular resistance and reduced compliance. Endothelial cell (EC) and vascular …

Chronic kidney disease (CKD) is common, with hypertension and diabetes mellitus acting as
major risk factors for its development. Cardiovascular disease is the leading cause of death …

Despite the critical impact of glaucoma on global blindness, its aetiology is not fully
characterised. Elevated intraocular pressure is highly associated with glaucomatous optic …