[HTML][HTML] Nanosystems in cardiovascular medicine: advancements, applications, and future perspectives

H Omidian, N Babanejad, LX Cubeddu - Pharmaceutics, 2023 - mdpi.com
Cardiovascular diseases (CVDs) remain a leading cause of morbidity and mortality globally.
Despite significant advancements in the development of pharmacological therapies, the …

Recent advancements in nanotechnology based drug delivery for the management of cardiovascular disease

A Ullah, M Ullah, SI Lim - Current problems in cardiology, 2024 - Elsevier
Cardiovascular diseases (CVDs) constitute a predominant cause of both global mortality
and morbidity. To address the challenges in the early diagnosis and management of CVDs …

Biomimetic platelet nanomotors for site-specific thrombolysis and ischemic injury alleviation

YT Chen, CH Liu, WY Pan, PR Jheng… - … applied materials & …, 2023 - ACS Publications
Due to the mortality associated with thrombosis and its high recurrence rate, there is a need
to investigate antithrombotic approaches. Noninvasive site-specific thrombolysis is a current …

Platelet Membrane Cloaked Nanotubes to Accelerate Thrombolysis by Thrombus Clot‐Targeting and Penetration

B Liu, F Victorelli, Y Yuan, Y Shen, H Hong, G Hou… - Small, 2023 - Wiley Online Library
Thrombotic diseases have a high rate of mortality and disability, and pose a serious threat to
global public health. Currently, most thrombolytic drugs especially protein drugs have a …

Multi-enzyme mimetic iridium nanozymes-based thrombus microenvironment-modulated nanoplatform for enhanced thrombolytic therapy

M Huang, Y Zhu, G **n, Y Wang, F Li, S Li… - Chemical Engineering …, 2023 - Elsevier
Intravenous injection of thrombolytic drugs is the most feasible strategy for the clinical
treatment of thrombotic diseases, however, its applications are yet limited by narrow …

Gamma-ray-responsive drug delivery systems for radiation protection

K Zheng, X Zhu, S Guo, X Zhang - Chemical Engineering Journal, 2023 - Elsevier
Undesirable exposures to the nuclear radiation will inevitably cause risks to human health,
and may result in carcinogenesis, organ failure and cell mutations. It is a long-standing and …

Organic Nanoparticles in Progressing Cardiovascular Disease Treatment and Diagnosis

AS Udriște, AC Burdușel, AG Niculescu, M Rădulescu… - Polymers, 2024 - mdpi.com
Cardiovascular diseases (CVDs), the world's most prominent cause of mortality, continue to
be challenging conditions for patients, physicians, and researchers alike. CVDs comprise a …

Recent advances in microfluidic technology of arterial thrombosis investigations

J Lin, S Chen, C Zhang, J Liao, Y Chen, S Deng, Z Mao… - Platelets, 2024 - Taylor & Francis
Microfluidic technology has emerged as a powerful tool in studying arterial thrombosis,
allowing researchers to construct artificial blood vessels and replicate the hemodynamics of …

[HTML][HTML] Clot‐targeted magnetic hyperthermia permeabilizes blood clots to make them more susceptible to thrombolysis

D Cabrera, ME Sharifabad, JA Ranjbar… - Journal of Thrombosis …, 2022 - Elsevier
Background Thrombolysis is a frontline treatment for stroke, which involves the application of
tissue plasminogen activator (tPA) to trigger endogenous clot‐degradation pathways …

[HTML][HTML] In Vitro Antithrombotic, Hematological Toxicity, and Inhibitor Studies of Protocatechuic, Isovanillic, and p-Hydroxybenzoic Acids from Maclura tricuspidata …

JH Choi, S Kim - Molecules, 2022 - mdpi.com
In blood coagulation, circulating platelets and coagulation factors are crucial for the primary
process because thrombi are generated by fibrin clotting with fibrinogen, thrombin, FXIIIa …