Monocytes and Macrophages in COVID-19
COVID-19 is a contagious viral disease caused by SARS-CoV-2 that led to an ongoing
pandemic with massive global health and socioeconomic consequences. The disease is …
pandemic with massive global health and socioeconomic consequences. The disease is …
Macrophages in lung injury, repair, and fibrosis
P Cheng, S Li, H Chen - Cells, 2021 - mdpi.com
Fibrosis progression in the lung commonly results in impaired functional gas exchange,
respiratory failure, or even death. In addition to the aberrant activation and differentiation of …
respiratory failure, or even death. In addition to the aberrant activation and differentiation of …
Cross-talk between alveolar macrophages and lung epithelial cells is essential to maintain lung homeostasis
EY Bissonnette, JF Lauzon-Joset, JS Debley… - Frontiers in …, 2020 - frontiersin.org
The main function of the lung is to perform gas exchange while maintaining lung
homeostasis despite environmental pathogenic and non-pathogenic elements contained in …
homeostasis despite environmental pathogenic and non-pathogenic elements contained in …
[HTML][HTML] Distinct developmental pathways from blood monocytes generate human lung macrophage diversity
E Evren, E Ringqvist, KP Tripathi, N Sleiers, IC Rives… - Immunity, 2021 - cell.com
The study of human macrophages and their ontogeny is an important unresolved issue.
Here, we use a humanized mouse model expressing human cytokines to dissect the …
Here, we use a humanized mouse model expressing human cytokines to dissect the …
Monocytes and macrophages in COVID-19: Friends and foes
The COVID-19 is a novel infectious disease caused by SARS-CoV-2 and is known as a
pandemic emergency that has led to a high rate of mortality throughout the world. Evidence …
pandemic emergency that has led to a high rate of mortality throughout the world. Evidence …
Ventilator-associated pneumonia: pathobiological heterogeneity and diagnostic challenges
F Howroyd, C Chacko, A MacDuff, N Gautam… - Nature …, 2024 - nature.com
Ventilator-associated pneumonia (VAP) affects up to 20% of critically ill patients and induces
significant antibiotic prescription pressure, accounting for half of all antibiotic use in the ICU …
significant antibiotic prescription pressure, accounting for half of all antibiotic use in the ICU …
Alveolar macrophages in lung inflammation and resolution
Macrophages and macrophage-like cells are present in all mammalian organs with
substantial heterogeneity and phenotypic specialization that is regulated in tissue-specific …
substantial heterogeneity and phenotypic specialization that is regulated in tissue-specific …
Functional polarization of tumor-associated macrophages dictated by metabolic reprogramming
W Zeng, F Li, S **, PC Ho, PS Liu, X **e - Journal of Experimental & …, 2023 - Springer
Macrophages are highly plastic in different tissues and can differentiate into functional
subpopulations under different stimuli. Tumor-associated macrophages (TAMs) are one of …
subpopulations under different stimuli. Tumor-associated macrophages (TAMs) are one of …
Origin and ontogeny of lung macrophages: from mice to humans
E Evren, E Ringqvist, T Willinger - Immunology, 2020 - Wiley Online Library
Macrophages are tissue‐resident myeloid cells with essential roles in host defense, tissue
repair, and organ homeostasis. The lung harbors a large number of macrophages that …
repair, and organ homeostasis. The lung harbors a large number of macrophages that …
Immunopathology of RSV: an updated review
RSV is a leading cause of respiratory tract disease in infants and the elderly. RSV has
limited therapeutic interventions and no FDA-approved vaccine. Gaps in our understanding …
limited therapeutic interventions and no FDA-approved vaccine. Gaps in our understanding …