Chitosan biomaterials application in dentistry

E Fakhri, H Eslami, P Maroufi, F Pakdel… - International journal of …, 2020 - Elsevier
Chitosan is a natural biopolymer derived from deacetylation of chitin and it has been
investigated with interdisciplinary approaches for multitude applications. Chitosan …

Advanced drug delivery approaches against periodontitis

D Joshi, T Garg, AK Goyal, G Rath - Drug delivery, 2016 - Taylor & Francis
Periodontitis is an inflammatory disease of gums involving the degeneration of periodontal
ligaments, creation of periodontal pocket and resorption of alveolar bone, resulting in the …

Dental delivery systems of antimicrobial drugs using chitosan, alginate, dextran, cellulose and other polysaccharides: A review

M Paul, SD Pramanik, RN Sahoo, YN Dey… - International Journal of …, 2023 - Elsevier
Dental caries, periodontal disease, and endodontic disease are major public health
concerns worldwide due to their impact on individuals' quality of life. The present problem of …

Polysaccharide-based drug delivery systems for the treatment of periodontitis

N Baranov, M Popa, LI Atanase, DL Ichim - Molecules, 2021 - mdpi.com
Periodontal diseases are worldwide health problems that negatively affect the lifestyle of
many people. The long-term effect of the classical treatments, including the mechanical …

Development and evaluation of biodegradable chitosan films of metronidazole and levofloxacin for the management of periodontitis

G Khan, SK Yadav, RR Patel, G Nath, M Bansal… - Aaps Pharmscitech, 2016 - Springer
Metronidazole (MZ) and levofloxacin (LF) are widely employed for treatment of periodontitis,
but high oral dose and resistance development after long-term oral administration limit their …

Recent trends in assessment of cellulose derivatives in designing novel and nanoparticulate-based drug delivery systems for improvement of oral health

KM Hosny, HM Alkhalidi, WS Alharbi, S Md, AM Sindi… - Polymers, 2021 - mdpi.com
Natural polymers are revolutionizing current pharmaceutical dosage forms design as
excipient and gained huge importance because of significant influence in formulation …

Development of doxycycline and atorvastatin-loaded chitosan nanoparticles for local delivery in periodontal disease

Y Yıldırım, İ İnce, B Gümüştaş, Ö Vardar, N Yakar… - Journal of Drug Delivery …, 2023 - Elsevier
The effectiveness of the local treatment depends on the ability of the release system to
deliver drugs efficiently as well as control of both infection and inflammation component of …

Polymer-based carriers in dental local healing—review and future challenges

D Kida, A Zakrzewska, J Zborowski, M Szulc… - Materials, 2021 - mdpi.com
Polymers in drug formulation technology and the engineering of biomaterials for the
treatment of oral diseases constitute a group of excipients that often possess additional …

Metronidazole-loaded porous matrices for local periodontitis treatment: In vitro evaluation and in vivo pilot study

D Kida, B Karolewicz, A Junka, A Sender-Janeczek… - Applied Sciences, 2019 - mdpi.com
Periodontal therapy focuses on thorough removal of subgingival calculus and plaque
products followed by the smoothing out of root surfaces. However, such conventional …