DrugCentral 2021 supports drug discovery and repositioning
DrugCentral is a public resource (http://drugcentral. org) that serves the scientific community
by providing up-to-date drug information, as described in previous papers. The current …
by providing up-to-date drug information, as described in previous papers. The current …
DrugCentral 2023 extends human clinical data and integrates veterinary drugs
DrugCentral monitors new drug approvals and standardizes drug information. The current
update contains 285 drugs (131 for human use). New additions include:(i) the integration of …
update contains 285 drugs (131 for human use). New additions include:(i) the integration of …
Overcoming antibiotic resistance: the potential and pitfalls of drug repurposing
M Abavisani, A Khoshrou, S Eshaghian… - Journal of Drug …, 2024 - Taylor & Francis
Since its emergence shortly after the discovery of penicillin, antibiotic resistance has
escalated dramatically, posing a significant health threat and economic burden. Drug …
escalated dramatically, posing a significant health threat and economic burden. Drug …
[HTML][HTML] Overview of the knowledge management center for illuminating the druggable genome
The Knowledge Management Center (KMC) for the Illuminating the Druggable Genome
(IDG) project aims to aggregate, update, and articulate protein-centric data knowledge for …
(IDG) project aims to aggregate, update, and articulate protein-centric data knowledge for …
Molecular Complexity: You Know It When You See It
Molecular complexity (MC) lacks a universal definition, but various studies address it in
contexts ranging from ligand–receptor interactions to DNA sequencing, with the overarching …
contexts ranging from ligand–receptor interactions to DNA sequencing, with the overarching …
SiSGC: A Drug Repositioning Prediction Model Based on Heterogeneous Simplifying Graph Convolution
Drug repositioning plays a key role in disease treatment. With the large-scale chemical data
increasing, many computational methods are utilized for drug–disease association …
increasing, many computational methods are utilized for drug–disease association …
COVID19-computational chemists meet the moment
As part of this response, since early 2020, numerous computational chemists and
biophysicists have pivoted their efforts to try to gain insight into the inner workings and …
biophysicists have pivoted their efforts to try to gain insight into the inner workings and …
Getting started with the IDG KMC datasets and tools
Abstract The Illuminating the Druggable Genome (IDG) consortium is a National Institutes of
Health (NIH) Common Fund program designed to enhance our knowledge of under‐studied …
Health (NIH) Common Fund program designed to enhance our knowledge of under‐studied …
Exploring DrugCentral: from molecular structures to clinical effects
Abstract DrugCentral, accessible at https://drugcentral. org, is an open-access online drug
information repository. It covers over 4950 drugs, incorporating structural, physicochemical …
information repository. It covers over 4950 drugs, incorporating structural, physicochemical …
Global barriers to accessing off-patent endocrine therapies: a renaissance of the orphan disease?
Context Clinical endocrinology encompasses many diseases requiring long-term drug
therapy. Prohibitive pricing of some endocrine drugs classified as essential by the World …
therapy. Prohibitive pricing of some endocrine drugs classified as essential by the World …