Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a devastating disease
that can be caused by a variety of conditions including pneumonia, sepsis, trauma, and most …

Abstract The coronavirus disease (COVID-19) has once again reminded us of the
significance of host immune response and consequential havocs of the immune …

Recent advances in microfluidic cell cultures enable the construction of in vitro human skin
models that can be used for drug toxicity testing, disease study. However, current in vitro …

Endothelial cells play a critical role in inflammation by responding to several endogenous
and exogenous proinflammatory stimuli. The three most studied factors that provide …

Understanding biological complexity arising from patterns of gene expression requires
accurate and precise measurement of RNA levels across large numbers of genes …

It is well established that chronic inflammation underpins the development of a number of
human cancers, with pro-inflammatory signaling within the tumor microenvironment …

Despite a positive correlation between chronic kidney disease and atherosclerosis, the
causative role of uremic toxins in leukocyte-endothelial interactions has not been reported …

As inflammation emerges as a risk factor for prostate cancer (PCa), there is potential for
chemoprevention by anti-inflammatory agents. Dietary phytochemicals have been shown to …

Endothelial-dependent mechanisms of mononuclear cell influx are not well understood. We
showed that acute stimulation of murine microvascular endothelial cells expressing the …

The formation of atherosclerotic plaque is a long and very complex process. The first signs of
development of atherosclerosis occur in areas where the blood vessels are strongly …