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[HTML][HTML] Essential metals in health and disease
In total, twenty elements appear to be essential for the correct functioning of the human
body, half of which are metals and half are non-metals. Among those metals that are …
body, half of which are metals and half are non-metals. Among those metals that are …
Prescribed drugs containing nitrogen heterocycles: an overview
Heteroatoms as well as heterocyclic scaffolds are frequently present as the common cores in
a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all …
a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all …
From purines to purinergic signalling: molecular functions and human diseases
Purines and their derivatives, most notably adenosine and ATP, are the key molecules
controlling intracellular energy homoeostasis and nucleotide synthesis. Besides, these …
controlling intracellular energy homoeostasis and nucleotide synthesis. Besides, these …
[HTML][HTML] Hegemony of inflammation in atherosclerosis and coronary artery disease
Inflammation drives coronary artery disease and atherosclerosis implications. Lipoprotein
entry, retention, and oxidative modification cause endothelial damage, triggering innate and …
entry, retention, and oxidative modification cause endothelial damage, triggering innate and …
Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis
J Wu, Z Wei, P Cheng, C Qian, F Xu, Y Yang… - …, 2020 - pmc.ncbi.nlm.nih.gov
Background: Gut microbiota, which plays a crucial role in inflammatory bowel diseases
(IBD), might have therapeutic benefits for ulcerative colitis or Crohn's disease. Targeting gut …
(IBD), might have therapeutic benefits for ulcerative colitis or Crohn's disease. Targeting gut …
The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
Sources of vascular nitric oxide and reactive oxygen species and their regulation
Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …
Oxidative stress in preeclampsia and placental diseases
Preeclampsia is a persistent hypertensive gestational disease characterized by high blood
pressure and proteinuria, which presents from the second trimester of pregnancy. At the …
pressure and proteinuria, which presents from the second trimester of pregnancy. At the …
5-Hydroxymethylfurfural (HMF) levels in honey and other food products: effects on bees and human health
An organic compound known as 5-hydroxymethylfurfural (HMF) is formed from reducing
sugars in honey and various processed foods in acidic environments when they are heated …
sugars in honey and various processed foods in acidic environments when they are heated …
Curcumin: an inflammasome silencer
Curcumin is the major bioactive polyphenolic ingredient of turmeric. Increasing evidence
indicates that the health benefits of curcumin are mediated through its anti-inflammatory and …
indicates that the health benefits of curcumin are mediated through its anti-inflammatory and …