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Adaptive immune resistance at the tumour site: mechanisms and therapeutic opportunities
TK Kim, EN Vandsemb, RS Herbst… - Nature Reviews Drug …, 2022 - nature.com
Tumours employ various tactics to adapt and eventually resist immune attack. These
mechanisms are collectively called adaptive immune resistance (AIR). The first defined and …
mechanisms are collectively called adaptive immune resistance (AIR). The first defined and …
Defining clinically useful biomarkers of immune checkpoint inhibitors in solid tumours
AM Holder, A Dedeilia, K Sierra-Davidson… - Nature Reviews …, 2024 - nature.com
Although more than a decade has passed since the approval of immune checkpoint
inhibitors (ICIs) for the treatment of melanoma and non-small-cell lung, breast and …
inhibitors (ICIs) for the treatment of melanoma and non-small-cell lung, breast and …
Transcriptome‐level discovery of survival‐associated biomarkers and therapy targets in non‐small‐cell lung cancer
B Győrffy - British journal of pharmacology, 2024 - Wiley Online Library
Abstract Background and Purpose Survival rate of patients with lung cancer has increased
by over 60% in the recent two decades. With longer survival, the identification of genes …
by over 60% in the recent two decades. With longer survival, the identification of genes …
[HTML][HTML] Digital pathology and artificial intelligence in translational medicine and clinical practice
V Baxi, R Edwards, M Montalto, S Saha - Modern Pathology, 2022 - Elsevier
Traditional pathology approaches have played an integral role in the delivery of diagnosis,
semi-quantitative or qualitative assessment of protein expression, and classification of …
semi-quantitative or qualitative assessment of protein expression, and classification of …
Cancer statistics, 2022
Abstract Each year, the American Cancer Society estimates the numbers of new cancer
cases and deaths in the United States and compiles the most recent data on population …
cases and deaths in the United States and compiles the most recent data on population …
Cancer statistics, 2021.
Each year, the American Cancer Society estimates the numbers of new cancer cases and
deaths in the United States and compiles the most recent data on population-based cancer …
deaths in the United States and compiles the most recent data on population-based cancer …
[HTML][HTML] Non-small cell lung cancer (NSCLC): A review of risk factors, diagnosis, and treatment
Y Alduais, H Zhang, F Fan, J Chen, B Chen - Medicine, 2023 - journals.lww.com
Lung cancer remains the leading cause of cancer deaths. Non-small cell lung cancer
(NSCLC) is the most frequent subtype of lung cancer. Surgery, radiation, chemotherapy …
(NSCLC) is the most frequent subtype of lung cancer. Surgery, radiation, chemotherapy …
At the crossroads of immunotherapy for oncogene-addicted subsets of NSCLC
I Otano, AC Ucero, J Zugazagoitia… - Nature reviews Clinical …, 2023 - nature.com
Non-small-cell lung cancer (NSCLC) has become a paradigm of precision medicine, with
the discovery of numerous disease subtypes defined by specific oncogenic driver mutations …
the discovery of numerous disease subtypes defined by specific oncogenic driver mutations …
Five-year outcomes from the randomized, phase III trials checkmate 017 and 057: nivolumab versus docetaxel in previously treated non–small-cell lung cancer
H Borghaei, S Gettinger, EE Vokes… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Immunotherapy has revolutionized the treatment of advanced non–small-cell
lung cancer (NSCLC). In two phase III trials (CheckMate 017 and CheckMate 057) …
lung cancer (NSCLC). In two phase III trials (CheckMate 017 and CheckMate 057) …
The effect of advances in lung-cancer treatment on population mortality
N Howlader, G Forjaz, MJ Mooradian… - … England Journal of …, 2020 - Mass Medical Soc
Background Lung cancer is made up of distinct subtypes, including non–small-cell lung
cancer (NSCLC) and small-cell lung cancer (SCLC). Although overall mortality from lung …
cancer (NSCLC) and small-cell lung cancer (SCLC). Although overall mortality from lung …