Carbonic anhydrases (CAs, EC 4.2. 1.1) are wide-spread zinc enzymes, present in archaeo-
and eubacteria, algae, green plants and animals. Within these organisms CAs are encoded …

Barometric pressure falls with increasing altitude and consequently there is a reduction in
the partial pressure of oxygen resulting in a hypoxic challenge to any individual ascending …

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Objective: To determine the incidence of acute mountain sickness in a general population of
visitors to moderate elevations, the characteristics associated with it, and its effect on …

Dihydropyridine calcium channel blockers (CCB) are typically used agents in the clinical
management of hypertension. Yet, they have also been utilized in the treatment of various …

Effective treatments for Coronavirus Disease 2019 (COVID-19) outbreak are urgently
needed. While anti-viral approaches and vaccines are being considered immediate …

OBJECTIVE--To assess the prevalence of symptoms and signs of acute mountain sickness
of the Swiss Alps. DESIGN--A study using an interview and clinical examination in a …

Acetazolamide, a potent carbonic anhydrase (CA) inhibitor, is the most commonly used and
best-studied agent for the amelioration of acute mountain sickness (AMS). The actual …

.—We hypothesized that exercise would cause greater severity and incidence of acute
mountain sickness (AMS) in the early hours of exposure to altitude. After passive ascent to …

Gastrointestinal complaints are often reported during ascents to high altitude (> 2,500 m),
though their etiology is not known. One potential explanation is injury to the intestinal barrier …