Drug resistance is mainly responsible for cancer recurrence and poor prognosis. Epigenetic
regulation is a heritable change in gene expressions independent of nucleotide sequence …

Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …

Importance Emerging data suggest that the incidence of early-onset cancers, defined as
cancers diagnosed in people younger than 50 years, is increasing, but updated data are …

China faces a disproportionate cancer burden to the population size and is undergoing a
transition in the cancer spectrum. We extracted data in five aspects of cancer incidence …

Colorectal carcinoma (CRC) is a common cause of mortality, but a comprehensive
description of its genomic landscape is lacking,,,,,,–. Here we perform whole-genome …

Objective This study aimed to explore the global burden of early-onset cancer based on the
Global Burden of Disease (GBD) 2019 study for 29 cancers worldwid. Methods and analysis …

Incidence and mortality of colorectal cancer (CRC) are increasing worldwide, suggesting
broad changes in the epidemiology of CRC. In this Review, we discuss the changes that are …

Epidemiologic data indicate a significant increase in the incidence of colorectal cancer in
younger populations in the past three decades. Moreover, recent evidence also …

Cancer has become a serious problem worldwide, as it represents the main cause of death,
and its incidence has increased over the years. A potential strategy to counter the growing …

Recent identification of oncogenic cells within healthy tissues and the prevalence of indolent
cancers found incidentally at autopsies reveal a greater complexity in tumor initiation than …