Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing
The brain requires a continuous supply of energy in the form of ATP, most of which is
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …
Parkinson's disease and gut microbiota: from clinical to mechanistic and therapeutic studies
X Zhang, B Tang, J Guo - Translational Neurodegeneration, 2023 - Springer
Parkinson's disease (PD) is one of the most prevalent neurodegenerative diseases. The
typical symptomatology of PD includes motor symptoms; however, a range of nonmotor …
typical symptomatology of PD includes motor symptoms; however, a range of nonmotor …
Insulin signaling impairment in the brain as a risk factor in Alzheimer's disease
C Hölscher - Frontiers in aging neuroscience, 2019 - frontiersin.org
Type 2 diabetes is a risk factor for develo** Alzheimer's disease (AD). The underlying
mechanism that links up the two conditions seems to be the de-sensitization of insulin …
mechanism that links up the two conditions seems to be the de-sensitization of insulin …
Effects of 3.5 GHz radiofrequency radiation on ghrelin, nesfatin-1, and irisin level in diabetic and healthy brains
Diabetes, mobile phone use, and obesity have increased simultaneously in recent years.
The radiofrequency radiation (RFR) emitted from mobile phones is largely absorbed in the …
The radiofrequency radiation (RFR) emitted from mobile phones is largely absorbed in the …
The emerging role of neuropeptides in Parkinson's disease
Y Zheng, L Zhang, J **e, L Shi - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
Parkinson's disease (PD), the second most common age-related neurodegenerative
disease, results from the loss of dopamine neurons in the substantia nigra. This disease is …
disease, results from the loss of dopamine neurons in the substantia nigra. This disease is …
The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice
Ghrelin is an orexigenic hormone that also plays an important role in mood disorders. Our
previous studies demonstrated that ghrelin administration could protect against depression …
previous studies demonstrated that ghrelin administration could protect against depression …
Acylated ghrelin as a multi-targeted therapy for Alzheimer's and Parkinson's disease
N Reich, C Hölscher - Frontiers in Neuroscience, 2020 - frontiersin.org
Much thought has been given to the impact of Amyloid Beta, Tau and Alpha-Synuclein in the
development of Alzheimer's disease (AD) and Parkinson's disease (PD), yet the clinical …
development of Alzheimer's disease (AD) and Parkinson's disease (PD), yet the clinical …
The interplay between ghrelin and microglia in neuroinflammation: implications for obesity and neurodegenerative diseases
C Russo, MS Valle, A Russo… - International Journal of …, 2022 - mdpi.com
Numerous studies have shown that microglia are capable of producing a wide range of
chemokines to promote inflammatory processes within the central nervous system (CNS) …
chemokines to promote inflammatory processes within the central nervous system (CNS) …
Ghrelin receptor signaling in health and disease: a biased view
As allosteric complexes, G-protein-coupled receptors (GPCRs) respond to extracellular
stimuli and pleiotropically couple to intracellular transducers to elicit signaling pathway …
stimuli and pleiotropically couple to intracellular transducers to elicit signaling pathway …
Ghrelin protects against rotenone-induced cytotoxicity: Involvement of mitophagy and the AMPK/SIRT1/PGC1α pathway
H Wang, S Dou, J Zhu, Z Shao, C Wang, X Xu… - Neuropeptides, 2021 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disorder,
characterized by the loss of dopaminergic neurons in the substantia nigra and the …
characterized by the loss of dopaminergic neurons in the substantia nigra and the …