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The hallmarks of cancer immune evasion
According to the widely accepted" three Es" model, the host immune system eliminates
malignant cell precursors and contains microscopic neoplasms in a dynamic equilibrium …
malignant cell precursors and contains microscopic neoplasms in a dynamic equilibrium …
CD36 as a gatekeeper of myocardial lipid metabolism and therapeutic target for metabolic disease
JFC Glatz, LC Heather… - Physiological reviews, 2024 - journals.physiology.org
The multifunctional membrane glycoprotein CD36 is expressed in different types of cells and
plays a key regulatory role in cellular lipid metabolism, especially in cardiac muscle. CD36 …
plays a key regulatory role in cellular lipid metabolism, especially in cardiac muscle. CD36 …
Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer
E Buglakova, M Ekelöf, M Schwaiger-Haber… - Nature …, 2024 - nature.com
While heterogeneity is a key feature of cancer, understanding metabolic heterogeneity at the
single-cell level remains a challenge. Here we present 13C-SpaceM, a method for spatial …
single-cell level remains a challenge. Here we present 13C-SpaceM, a method for spatial …
Lactylated apolipoprotein C‐II induces immunotherapy resistance by promoting extracellular lipolysis
J Chen, D Zhao, Y Wang, M Liu, Y Zhang… - Advanced …, 2024 - Wiley Online Library
Mortality rates due to lung cancer are high worldwide. Although PD‐1 and PD‐L1 immune
checkpoint inhibitors boost the survival of patients with non‐small‐cell lung cancer …
checkpoint inhibitors boost the survival of patients with non‐small‐cell lung cancer …
Review of eukaryote cellular membrane lipid Composition, with special attention to the fatty acids
Biological membranes, primarily composed of lipids, envelop each living cell. The intricate
composition and organization of membrane lipids, including the variety of fatty acids they …
composition and organization of membrane lipids, including the variety of fatty acids they …
Plastic residues alter soil microbial community compositions and metabolite profiles under realistic conditions
D Dong, Z Guo, F Wu, X Yang, J Li - Science of The Total Environment, 2024 - Elsevier
Wide usage of plastic coupled with mismanagement has created a humongous
environmental hazard threatening entire ecosystems. To date, the potential effects of plastic …
environmental hazard threatening entire ecosystems. To date, the potential effects of plastic …
Metabolic effects of ketogenic diets: exploring whole-body metabolism in connection with adipose tissue and other metabolic organs
Y Ahmad, DS Seo, Y Jang - International Journal of Molecular Sciences, 2024 - mdpi.com
The ketogenic diet (KD) is characterized by minimal carbohydrate, moderate protein, and
high fat intake, leading to ketosis. It is recognized for its efficiency in weight loss, metabolic …
high fat intake, leading to ketosis. It is recognized for its efficiency in weight loss, metabolic …
Disorders of fatty acid homeostasis
FM Vaz, S Ferdinandusse, GS Salomons… - Journal of Inherited …, 2025 - Wiley Online Library
Humans derive fatty acids (FA) from exogenous dietary sources and/or endogenous
synthesis from acetyl‐CoA, although some FA are solely derived from exogenous sources …
synthesis from acetyl‐CoA, although some FA are solely derived from exogenous sources …
Molecular drug simulation and experimental validation of the CD36 receptor competitively binding to Long-Chain fatty acids by 7-Ketocholesteryl-9-carboxynonanoate
C Fu, ML **ang, S Chen, G Dong, Z Liu, CB Chen… - ACS …, 2023 - ACS Publications
Long-chain fatty acids (LCFAs) are one of the main energy-supplying substances in the
body. LCFAs with different lengths and saturations may have contrasting biological effects …
body. LCFAs with different lengths and saturations may have contrasting biological effects …
The membrane domains of mammalian adenylyl cyclases are lipid receptors
M Landau, S Elsabbagh, H Gross, ACD Fuchs… - elife, 2024 - elifesciences.org
Abstract The biosynthesis of cyclic 3′, 5′-adenosine monophosphate (cAMP) by
mammalian membrane-bound adenylyl cyclases (mACs) is predominantly regulated by G …
mammalian membrane-bound adenylyl cyclases (mACs) is predominantly regulated by G …