Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies

M Vargas-Soria, M García-Alloza… - Journal of …, 2023 - Springer
Diabetes mellitus is a heterogeneous chronic metabolic disorder characterized by the
presence of hyperglycemia, commonly preceded by a prediabetic state. The excess of blood …

[HTML][HTML] Untangling the extracellular matrix of idiopathic epiretinal membrane: a path winding among structure, interactomics and translational medicine

L Bianchi, A Altera, V Barone, D Bonente, T Bacci… - Cells, 2022 - mdpi.com
Idiopathic epiretinal membranes (iERMs) are fibrocellular sheets of tissue that develop at the
vitreoretinal interface. The iERMs consist of cells and an extracellular matrix (ECM) formed …

Single-cell transcriptomics reveals novel role of microglia in fibrovascular membrane of proliferative diabetic retinopathy

Z Hu, X Mao, M Chen, X Wu, T Zhu, Y Liu, Z Zhang… - Diabetes, 2022 - diabetesjournals.org
Vitreous fibrovascular membranes (FVMs), the hallmark of proliferative diabetic retinopathy
(PDR), cause retinal hemorrhage, detachment, and eventually blindness. However, little is …

Pathophysiology and clinical aspects of epiretinal membrane–review

MK Ożóg, M Nowak-Wąs, W Rokicki - Frontiers in Medicine, 2023 - frontiersin.org
The epiretinal membrane (ERM) is a pathological tissue formed at the vitreoretinal interface.
The formation of this tissue is associated with numerous symptoms related to disturbances of …

Oxidative stress in diabetic retinopathy

ÁL Ortega - Antioxidants, 2021 - mdpi.com
Diabetic Retinopathy (DR) is a progressive asymptomatic neuro-vascular complication of
diabetes that triggers irreversible retinal damage. This common complication is the leading …

[HTML][HTML] Aqueous Humor Cytokines in Idiopathic Epiretinal Membrane: Correlation with Disease Severity

T Torresin, A Greggio, R Frisina, L Motta, I Gius… - Diagnostics, 2024 - mdpi.com
Background: To analyze the concentration of aqueous humor (AH) cytokines in eyes with
idiopathic epiretinal membrane (iERM) and to investigate their potential correlation with …

Assessment of protein profile in vitreous samples of patients with epiretinal membrane by proteomic approaches

F Sumer, B Ozkan, VL Karabas, G Akpinar… - Experimental Eye …, 2025 - Elsevier
This study aims to characterize idiopathic epiretinal membrane (iERM) using proteomic
analysis to enhance diagnosis and treatment strategies. In a prospective case-control …

Short‐Term In Vitro ROS Detection and Oxidative Stress Regulators in Epiretinal Membranes and Vitreous from Idiopathic Vitreoretinal Diseases

BO Balzamino, L Dinice, A Cacciamani… - BioMed Research …, 2022 - Wiley Online Library
Background. A plethora of inflammatory, angiogenic, and tissue remodeling factors has
been reported in idiopathic epiretinal membranes (ERMs). Herein we focused on the …

Optical coherence tomography characteristics over time in Behçet's uveitis

R Liang, L Yang, S Zeng, X Liu - Retina, 2023 - journals.lww.com
Purpose: To analyze the characteristics of macular optical coherence tomography in patients
with Behçet's uveitis (BU). Methods: Retrospectively analyzing optical coherence …

Hyperuricemia and epiretinal pathologies: a review of pathophysiological links and clinical implications

CY Cheng, JC Liu, HY Chen, JJ Chen… - Exploration of …, 2024 - explorationpub.com
Hyperuricemia (HUA), defined by elevated serum uric acid levels, is well-established in its
association with systemic conditions like gout and cardiovascular diseases. Recently …