Exosome-driven nano-immunotherapy: revolutionizing colorectal cancer treatment
Colorectal cancer (CRC) ranks as the third most common cancer worldwide and remains a
major cause of cancer-related deaths, necessitating the development of innovative …
major cause of cancer-related deaths, necessitating the development of innovative …
[HTML][HTML] Development of small molecule drugs targeting immune checkpoints
L Chen, X Zhao, X Liu, Y Ouyang, C Xu… - Cancer Biology & …, 2024 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are used to relieve and refuel anti-tumor immunity by
blocking the interaction, transcription, and translation of co-inhibitory immune checkpoints or …
blocking the interaction, transcription, and translation of co-inhibitory immune checkpoints or …
Docosahexaenoic acid (DHA) impairs hypoxia-induced cellular and exosomal overexpression of immune-checkpoints and immunomodulatory molecules in different …
Background Tumor cells express immune-checkpoint molecules to suppress anti-tumor
immune responses. In part, immune evasion takes place by secreting exosomes bearing …
immune responses. In part, immune evasion takes place by secreting exosomes bearing …