HIV-1 has evolved multiple mechanisms to elude immune control. The view of virus as
classifiable into distinct subtypes needs to reflect the reality of the constant emergence of …

Evolutionary modelling studies indicate less than a century has passed since the most
recent common ancestor of the HIV-1 pandemic strains and, in that time frame, an …

Antibodies capable of neutralizing HIV-1 often target variable regions 1 and 2 (V1V2) of the
HIV-1 envelope, but the mechanism of their elicitation has been unclear. Here we define the …

The development of an effective human immunodeficiency virus type 1 (HIV-1) vaccine is
likely to depend on knowledge of circulating variants of genes other than the commonly …

HIV-1 sequences were analyzed to estimate the timing of the ancestral sequence of the
main group of HIV-1, the strains responsible for the AIDS pandemic. Using parallel …

A clear and consistent genetic classification of human immunodeficiency virus-type 1 (HIV-1)
strains continues to be of great utility in epidemiological tracking of the AIDS pandemic and …

Human immunodeficiency virus type 1 (HIV-1) is the causative agent of AIDS (10, 38, 105,
114). It is characterized by extensive and dynamic genetic diversity, generating variants …

Objectives: We sought to comprehensively analyze the origin, transmission patterns and sub-
epidemic clusters of the HIV-1 CRF01_AE strains in China. Methods: Available HIV-1 …

The diploid nature of human immunodeficiency virus type 1 (HIV-1) indicates that
recombination serves a central function in virus replication and evolution. Previously, while …

At least 10 different genetic human immunodeficiency virus type 1 (HIV-1) subtypes (A—J)
are responsible for the AIDS pandemic. Much of the understanding of HIV-1 disease …