Magnetite nanoparticles in magnetic hyperthermia and cancer therapies: Challenges and perspectives

A Włodarczyk, S Gorgoń, A Radoń, K Bajdak-Rusinek - Nanomaterials, 2022 - mdpi.com
Until now, strategies used to treat cancer are imperfect, and this generates the need to
search for better and safer solutions. The biggest issue is the lack of selective interaction …

DNA nanotechnology-enabled drug delivery systems

Q Hu, H Li, L Wang, H Gu, C Fan - Chemical reviews, 2018 - ACS Publications
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases

D Furtado, M Björnmalm, S Ayton, AI Bush… - Advanced …, 2018 - Wiley Online Library
Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …

Pharmacokinetics of magnetic iron oxide nanoparticles for medical applications

J Nowak-Jary, B Machnicka - Journal of Nanobiotechnology, 2022 - Springer
Magnetic iron oxide nanoparticles (MNPs) have been under intense investigation for at least
the last five decades as they show enormous potential for many biomedical applications …

Ligand‐installed nanocarriers toward precision therapy

P Mi, H Cabral, K Kataoka - Advanced Materials, 2020 - Wiley Online Library
Abstract Development of drug‐delivery systems that selectively target neoplastic cells has
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …

Brain‐targeted liposomes loaded with monoclonal antibodies reduce alpha‐synuclein aggregation and improve behavioral symptoms in Parkinson's disease

M Sela, M Poley, P Mora‐Raimundo… - Advanced …, 2023 - Wiley Online Library
Monoclonal antibodies (mAbs) hold promise in treating Parkinson's disease (PD), although
poor delivery to the brain hinders their therapeutic application. In the current study, it is …

In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles

H Arami, A Khandhar, D Liggitt… - Chemical Society …, 2015 - pubs.rsc.org
Iron oxide nanoparticles (IONPs) have been extensively used during the last two decades,
either as effective bio-imaging contrast agents or as carriers of biomolecules such as drugs …

H2O2-responsive liposomal nanoprobe for photoacoustic inflammation imaging and tumor theranostics via in vivo chromogenic assay

Q Chen, C Liang, X Sun, J Chen… - Proceedings of the …, 2017 - National Acad Sciences
Abnormal H2O2 levels are closely related to many diseases, including inflammation and
cancers. Herein, we simultaneously load HRP and its substrate, 2, 2′-azino-bis (3 …

[HTML][HTML] Magnetite nanoparticles for cancer diagnosis, treatment, and treatment monitoring: recent advances

RA Revia, M Zhang - Materials today, 2016 - Elsevier
The development of nanoparticles (NPs) for use in all facets of oncological disease
detection and therapy has shown great progress over the past two decades. NPs have been …

Synthesis, bioapplications, and toxicity evaluation of chitosan-based nanoparticles

BR Rizeq, NN Younes, K Rasool… - International journal of …, 2019 - mdpi.com
The development of advanced nanomaterials and technologies is essential in biomedical
engineering to improve the quality of life. Chitosan-based nanomaterials are on the forefront …