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Pioglitazone and bladder cancer risk: a systematic review and meta‐analysis
Current evidence about the association between pioglitazone and bladder cancer risk
remains conflict. We aimed to assess the risk of bladder cancer associated with the use of …
remains conflict. We aimed to assess the risk of bladder cancer associated with the use of …
PPARs and tumor microenvironment: the emerging roles of the metabolic master regulators in tumor stromal–epithelial crosstalk and carcinogenesis
Simple Summary The roles of peroxisome proliferator-activated receptors (PPARs) in
carcinogenesis are increasingly appreciated. With the growing interest in tumor stromal …
carcinogenesis are increasingly appreciated. With the growing interest in tumor stromal …
[HTML][HTML] PPAR-γ partial agonists in disease-fate decision with special reference to cancer
Peroxisome proliferator-activated receptor-γ (PPAR-γ) has emerged as one of the most
extensively studied transcription factors since its discovery in 1990, highlighting its …
extensively studied transcription factors since its discovery in 1990, highlighting its …
The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity
Peroxisome proliferator-activated receptor γ (PPARγ) belongs to the nuclear receptor
superfamily of PPARs (PPARα, PPARβ/δ, PPARγ). Numerous studies have concentrated on …
superfamily of PPARs (PPARα, PPARβ/δ, PPARγ). Numerous studies have concentrated on …
Ipragliflozin additively ameliorates non-alcoholic fatty liver disease in patients with type 2 diabetes controlled with metformin and pioglitazone: a 24-week randomized …
Despite the benefits of pioglitazone in the treatment of non-alcoholic fatty liver disease
(NAFLD), many treated patients continue to experience disease progression. We aimed to …
(NAFLD), many treated patients continue to experience disease progression. We aimed to …
PPARγ agonist pioglitazone enhances colorectal cancer immunotherapy by inducing PD-L1 autophagic degradation
X Jia, J Qian, H Chen, Q Liu, S Hussain, J **… - European Journal of …, 2023 - Elsevier
Abstract Blockade of PD-1/PD-L1 immune checkpoint could be an effective antitumor
strategy for multiple types of cancer, but it is low response rate for colorectal cancer patients …
strategy for multiple types of cancer, but it is low response rate for colorectal cancer patients …
PPARγ inhibited tumor immune escape by inducing PD‐L1 autophagic degradation
Q Gou, S Che, M Chen, H Chen, J Shi, Y Hou - Cancer Science, 2023 - Wiley Online Library
Blockade of the programmed death 1 (PD‐1)/programmed death ligand 1 (PD‐L1) immune
checkpoint could increase antitumor immunotherapy for multiple types of cancer, but the …
checkpoint could increase antitumor immunotherapy for multiple types of cancer, but the …
[HTML][HTML] Peroxisomes and PPARs: emerging role as master regulators of cancer metabolism
Cancer is a disease characterized by the acquisition of a multitude of unique traits. It has
long been understood that cancer cells divert significantly from normal cell metabolism. The …
long been understood that cancer cells divert significantly from normal cell metabolism. The …
An update review of post‐transplant diabetes mellitus: concept, risk factors, clinical implications and management
Objective Kidney transplantation is the gold standard therapeutic alternative for patients with
end‐stage renal disease; nevertheless, it is not without potential complications leading to …
end‐stage renal disease; nevertheless, it is not without potential complications leading to …
Effect of statin on hepatocellular carcinoma in patients with type 2 diabetes: a nationwide nested case‐control study
Relationship on new statin use and the risk of hepatocellular carcinoma (HCC) in patients
with incident type 2 diabetes mellitus (T2DM), who might be at the risk of develo** HCC, is …
with incident type 2 diabetes mellitus (T2DM), who might be at the risk of develo** HCC, is …