Pioglitazone and bladder cancer risk: a systematic review and meta‐analysis

H Tang, W Shi, S Fu, T Wang, S Zhai, Y Song… - Cancer …, 2018 - Wiley Online Library
Current evidence about the association between pioglitazone and bladder cancer risk
remains conflict. We aimed to assess the risk of bladder cancer associated with the use of …

PPARs and tumor microenvironment: the emerging roles of the metabolic master regulators in tumor stromal–epithelial crosstalk and carcinogenesis

HS Cheng, YS Yip, EKY Lim, W Wahli, NS Tan - Cancers, 2021 - mdpi.com
Simple Summary The roles of peroxisome proliferator-activated receptors (PPARs) in
carcinogenesis are increasingly appreciated. With the growing interest in tumor stromal …

[HTML][HTML] PPAR-γ partial agonists in disease-fate decision with special reference to cancer

S Ballav, B Biswas, VK Sahu, A Ranjan, S Basu - Cells, 2022 - mdpi.com
Peroxisome proliferator-activated receptor-γ (PPAR-γ) has emerged as one of the most
extensively studied transcription factors since its discovery in 1990, highlighting its …

The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity

S Yousefnia, S Momenzadeh, FS Forootan, K Ghaedi… - Gene, 2018 - Elsevier
Peroxisome proliferator-activated receptor γ (PPARγ) belongs to the nuclear receptor
superfamily of PPARs (PPARα, PPARβ/δ, PPARγ). Numerous studies have concentrated on …

Ipragliflozin additively ameliorates non-alcoholic fatty liver disease in patients with type 2 diabetes controlled with metformin and pioglitazone: a 24-week randomized …

E Han, Y Lee, BW Lee, ES Kang, BS Cha - Journal of clinical medicine, 2020 - mdpi.com
Despite the benefits of pioglitazone in the treatment of non-alcoholic fatty liver disease
(NAFLD), many treated patients continue to experience disease progression. We aimed to …

PPARγ agonist pioglitazone enhances colorectal cancer immunotherapy by inducing PD-L1 autophagic degradation

X Jia, J Qian, H Chen, Q Liu, S Hussain, J **… - European Journal of …, 2023 - Elsevier
Abstract Blockade of PD-1/PD-L1 immune checkpoint could be an effective antitumor
strategy for multiple types of cancer, but it is low response rate for colorectal cancer patients …

PPARγ inhibited tumor immune escape by inducing PD‐L1 autophagic degradation

Q Gou, S Che, M Chen, H Chen, J Shi, Y Hou - Cancer Science, 2023 - Wiley Online Library
Blockade of the programmed death 1 (PD‐1)/programmed death ligand 1 (PD‐L1) immune
checkpoint could increase antitumor immunotherapy for multiple types of cancer, but the …

[HTML][HTML] Peroxisomes and PPARs: emerging role as master regulators of cancer metabolism

AM Pratama, M Sharma, S Naidu, H Bömmel… - Molecular …, 2024 - Elsevier
Cancer is a disease characterized by the acquisition of a multitude of unique traits. It has
long been understood that cancer cells divert significantly from normal cell metabolism. The …

An update review of post‐transplant diabetes mellitus: concept, risk factors, clinical implications and management

M Kanbay, S Copur, AU Topçu… - Diabetes, Obesity …, 2024 - Wiley Online Library
Objective Kidney transplantation is the gold standard therapeutic alternative for patients with
end‐stage renal disease; nevertheless, it is not without potential complications leading to …

Effect of statin on hepatocellular carcinoma in patients with type 2 diabetes: a nationwide nested case‐control study

G Kim, SY Jang, E Han, Y Lee, S Park… - … journal of cancer, 2017 - Wiley Online Library
Relationship on new statin use and the risk of hepatocellular carcinoma (HCC) in patients
with incident type 2 diabetes mellitus (T2DM), who might be at the risk of develo** HCC, is …