Corticostriatal projections are essential components of forebrain circuits and are widely
involved in motivated behaviour. These axonal projections are formed by two distinct …

The midbrain dopamine (DA) neurons play a central role in develo** appropriate goal-
directed behaviors, including the motivation and cognition to develop appropriate actions to …

We all have a sense of time. Yet, there are no sensory receptors specifically dedicated for
perceiving time. It is an almost uniquely intangible sensation: we cannot see time in the way …

Although cortico-striato-thalamo-cortical (CSTC) circuit dysregulation is correlated with
obsessive compulsive disorder (OCD), causation cannot be tested in humans. We used …

Midbrain dopamine neurons are an essential component of the basal ganglia circuitry,
playing key roles in the control of fine movement and reward. Recently, it has been …

Motivational relevance can prioritize information for memory encoding and consolidation
based on reward value. In this review, we pinpoint the possible psychological and neural …

Background Obsessive-compulsive disorder (OCD) is associated with regional hyperactivity
in cortico-striatal circuits. However, the large-scale patterns of abnormal neural connectivity …

Appetitive motivation and incentive states are essential functions sustained by a common
emotional brain process, the SEEKING disposition, which drives explorative and approach …

The hippocampal formation and striatum subserve declarative and procedural memory,
respectively. However, experimental evidence suggests that the ventral striatum, as …

A network of brain structures including hippocampus (HC), prefrontal cortex, and striatum
controls goal-directed behavior and decision making. However, the neural mechanisms …