Outcomes of kidney perfusion techniques in transplantation from deceased donors: a systematic review and meta-analysis

AS Ghoneima, RX Sousa Da Silva, MA Gosteli… - Journal of Clinical …, 2023 - mdpi.com
The high demand for organs in kidney transplantation and the expansion of the donor pool
have led to the widespread implementation of machine perfusion technologies. In this study …

Perfusion Techniques in Kidney Allograft Preservation to Reduce Ischemic Reperfusion Injury: A Systematic Review and Meta-Analysis

BJ Hasjim, JM Sanders, M Alexander, RR Redfield III… - Antioxidants, 2024 - mdpi.com
The limited supply and rising demand for kidney transplantation has led to the use of
allografts more susceptible to ischemic reperfusion injury (IRI) and oxidative stress to …

Waitlist and transplant outcomes in organ donation after circulatory death: trends in the United States

JH Kwon, WM Blanding, K Shorbaji, JR Scalea… - Annals of …, 2023 - journals.lww.com
Objectives: To summarize waitlist and transplant outcomes in kidney, liver, lung, and heart
transplantation using organ donation after circulatory death (DCD). Background: DCD has …

Outcomes of combined heart and kidney transplantation under the new heart allocation policy: a united organ network for organ sharing database analysis

S Ohira, K Okumura, S Pan, A Dhand… - Circulation: Heart …, 2023 - ahajournals.org
Background: The impact of the new heart allocation policy, which prioritizes acutely ill
patients on temporary mechanical circulatory support and provides broader sharing of donor …

Complement-targeting therapeutics for ischemia-reperfusion injury in transplantation and the potential for ex vivo delivery

IF Delaura, Q Gao, IJ Anwar, N Abraham… - Frontiers in …, 2022 - frontiersin.org
Organ shortages and an expanding waitlist have led to increased utilization of marginal
organs. All donor organs are subject to varying degrees of IRI during the transplant process …

Prediction of delayed graft function by early salivary microbiota following kidney transplantation

X **ang, B Peng, K Liu, T Wang, P Ding, Y Zhu… - Applied Microbiology …, 2024 - Springer
Delayed graft function (DGF) is a frequently observed complication following kidney
transplantation (KT). Our prior research revealed dynamic shifts in salivary microbiota post …

Appraisal of donation after circulatory death: how far could we expand the heart donor pool?

A Suarez-Pierre, J Iguidbashian, C Stuart… - The Annals of Thoracic …, 2022 - Elsevier
Background the incidence of organ donation after circulatory death (DCD) is increasing;
however, heart use has lagged behind other solid organs. Ex vivo perfusion devices are …

[HTML][HTML] Complement activation and kidney transplantation; a complex relationship

B Gibson, C Connelly, S Moldakhmetova, NS Sheerin - Immunobiology, 2023 - Elsevier
Although kidney transplantation is the best treatment for end stage kidney disease, the
benefits are limited by factors such as the short fall in donor numbers, the burden of …

How to best protect kidneys for transplantation—Mechanistic target

S Akalay, SA Hosgood - Journal of Clinical Medicine, 2023 - mdpi.com
The increasing number of patients on the kidney transplant waiting list underlines the need
to expand the donor pool and improve kidney graft utilization. By protecting kidney grafts …

From haphazard to a sustainable normothermic regional perfusion service: a blueprint for the introduction of novel perfusion technologies

F Hunt, CJC Johnston, L Coutts… - Transplant …, 2022 - frontierspartnerships.org
Normothermic Regional Perfusion (NRP) has shown encouraging clinical results. However,
translation from an experimental to routine procedure poses several challenges. Herein we …