Among FOS-related components of the dimeric AP-1 transcription factor, the oncoprotein
FRA-1 (encoded by FOSL1) is a key regulator of invasion and metastasis. The well …

Abstract The Activator Protein 1 (AP-1) transcription factor complex plays a pivotal role in the
regulation of cancer-related genes, influencing cancer cell proliferation, invasion, migration …

Irisin is an exercise-induced myokine that alleviates inflammation and obesity. The induction
of anti-inflammatory (M2) macrophage is facilitated for treatment of sepsis and associated …

Increased expression of AP-1 transcription factor components has been reported in acute
kidney injury (AKI). However, the role of specific components, such as Fosl1, in tubular cells …

FRA1 (FOSL1) is a transcription factor and a member of the activator protein-1 superfamily.
FRA1 is expressed in most tissues at low levels, and its expression is robustly induced in …

Fra-1 (Fos-related antigen1), a member of transcription factor activator protein (AP-1), plays
an important role in cell proliferation, apoptosis, differentiation, inflammation, oncogenesis …

Psoriasis is a common and immune-mediated skin disease related to keratinocytes
hyperproliferation and inflammation. Fos-like antigen-1 (FOSL1) is an important transcription …

In recent years, inflammatory disorders have emerged as a significant concern for human
health. Through ongoing research on anti‐inflammatory agents, alpinetin has shown …

Introduction Munro's microabscess is a typical pathological feature in the early psoriatic
lesion, mainly characterized by the accumulation of neutrophils in the epidermis. DNA …

Objectives. Excessive inflammatory responses and reactive oxygen species (ROS) formation
play pivotal roles in the pathogenesis of sepsis. Penfluroidol (PF), an oral long‐acting …