Darunavir/cobicistat for the treatment of HIV-1: a new era for compact drugs with high genetic barrier to resistance

A Capetti, MV Cossu, G Rizzardini - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Cobicistat-boosted darunavir is a boosted protease inhibitor in a fixed-dose
combination to be approved for the treatment of human immunodeficiency virus type1 …

Major Drug Resistance Mutations on Reverse Transcriptase Gene in Human Immunodeficiency Virus Type-1 in Indonesia: A Systematic Review

Nurjannah, S Jayanti, FS Tanoerahardjo… - Current HIV/AIDS …, 2024 - Springer
Abstract Purpose of Review The prevalence of HIV-1 in Indonesia is on a concerning
upward trajectory, with a concurrent rise in the development of drug-resistant strains …

[HTML][HTML] Prevalence of HIV infection and resistance mutations in patients hospitalized for febrile illness in Indonesia

TP Merati, M Karyana, E Tjitra, H Kosasih… - The American Journal …, 2021 - ncbi.nlm.nih.gov
HIV prevalence in Indonesia is increasing, and only 64% of infected individuals know their
status. In a prospective cohort of 1,453 hospitalized patients with unexplained fever, 46 …

[HTML][HTML] Prevalence of major INSTI and HIV-1 drug resistance mutations in pre-and antiretroviral-treated patients in Indonesia

FA Djojosugito, A Arfianti, R Wisaksana, FM Siregar… - Narra J, 2024 - pmc.ncbi.nlm.nih.gov
Indonesia has one of the highest HIV infection rates in Southeast Asia. The use of
dolutegravir, an integrase strand transfer inhibitor (INSTI), as a first-line treatment …

Spatial–temporal transmission dynamics of HIV-1 CRF01_AE in Indonesia

SQ Khairunisa, DW Indriati, NLA Megasari, S Ueda… - Scientific Reports, 2024 - nature.com
Human immunodeficiency virus type 1 (HIV-1) remains a serious health threat in Indonesia.
In particular, the CRF01_AE viruses were the predominant HIV-1 strains in various cities in …

Genetic diversity and drug resistance of HIV-1 circulating in North Sulawesi, Indonesia

S Ueda, AM Witaningrum, SQ Khairunisa… - AIDS research and …, 2019 - liebertpub.com
Manado, the capital city of North Sulawesi, is a unique region in Indonesia because of its
religion. We collected peripheral blood samples from 63 individuals on antiretroviral therapy …

[HTML][HTML] Identification of HIV-1 subtypes and drug resistance mutations among HIV-1-infected individuals residing in Pontianak, Indonesia

SQ Khairunisa, NLA Megasari, DW Indriati, T Kotaki… - Germs, 2020 - ncbi.nlm.nih.gov
Methods Whole blood samples collected from 30 HIV-1-infected individuals, comprising 19
ART-experienced and 11 ART-naïve individuals, were subjected to RNA and DNA …

Genotypic characterization of human immunodeficiency virus type 1 derived from antiretroviral therapy-naive individuals residing in Sorong, West Papua

AM Witaningrum, T Kotaki, SQ Khairunisa… - AIDS research and …, 2016 - liebertpub.com
Abstract Papua and West Papua provinces have the highest prevalence rate of human
immunodeficiency virus type 1 (HIV-1) infection in Indonesia; however, data on the …

The emergence of HIV-1 transmitted drug resistance mutations among antiretroviral therapy-naive individuals in Buleleng, Bali, Indonesia

NLA Megasari, D Oktafiani, E Fitriana… - Acta Medica …, 2019 - actamedindones.org
Background: the global scale-up of antiretroviral therapy (ART) is the primary factor
contributing to the decline in deaths from acquired immune deficiency syndrome (AIDS) …

Genotypic characterization of human immunodeficiency virus type 1 prevalent in Kepulauan Riau, Indonesia

SQ Khairunisa, S Ueda, AM Witaningrum… - AIDS Research and …, 2018 - liebertpub.com
Kepulauan Riau is a famous tourist destination in Indonesia. The epidemic of human
immunodeficiency virus type 1 (HIV-1) infection is gradually increasing in this region. We …