Galectins, a family of evolutionarily conserved glycan-binding proteins, play key roles in
diverse biological processes including tissue repair, adipogenesis, immune cell …

Cancer nanovaccines as one of immunotherapeutic approaches are able to attack tumors by
stimulating tumor-specific immunological responses. However, there still exist multiple …

Galectins, an ancient lectin family, are characterized by specific binding of β-galactosides
through evolutionary conserved sequence elements of carbohydrate-recognition domain …

Aberrant glycosylation expressed in glycosphingolipids and glycoproteins in tumor cells has
been implicated as an essential mechanism in defining stage, direction, and fate of tumor …

Galectins are cytosolic proteins that lack any signal sequence for transport into the
endoplasmic reticulum and are not glycosylated, although several galectins contain …

Glycosylation of glycoproteins and glycolipids is one of many molecular changes that
accompany malignant transformation. GlcNAc-branched N-glycans and terminal Lewis …

Mucins are high-molecular weight epithelial glycoproteins with a high content of clustered
oligosaccharides O-glycosidically linked to tandem repeat peptides rich in threonine, serine …

Nanotechnology is a field of research at the crossroads of biology, chemistry, physics,
engineering, and medicine. Design of multifunctional nanoparticles capable of targeting …

Recent studies have shown that a carbohydrate-binding protein, galectin-3, is a novel pro-
angiogenic molecule. The mechanism by which galectin-3 promotes angiogenesis remains …

Lectins, or carbohydrate binding proteins, recognize specific oligosaccharide structures on
glycoproteins and glycolipids. Several families of animal lectins have been identified; for …