Strategies for the one-step immobilization–purification of enzymes as industrial biocatalysts

O Barbosa, C Ortiz, Á Berenguer-Murcia, R Torres… - Biotechnology …, 2015 - Elsevier
In this review, we detail the efforts performed to couple the purification and the
immobilization of industrial enzymes in a single step. The use of antibodies, the …

[HTML][HTML] Orientation and characterization of immobilized antibodies for improved immunoassays

NG Welch, JA Scoble, BW Muir, PJ Pigram - Biointerphases, 2017 - pubs.aip.org
Orientation of surface immobilized capture proteins, such as antibodies, plays a critical role
in the performance of immunoassays. The sensitivity of immunodiagnostic procedures is …

Control of protein immobilization: Coupling immobilization and site-directed mutagenesis to improve biocatalyst or biosensor performance

K Hernandez, R Fernandez-Lafuente - Enzyme and microbial technology, 2011 - Elsevier
Mutagenesis and immobilization are usually considered to be unrelated techniques with
potential applications to improve protein properties. However, there are several reports …

Site-directed antibody immobilization techniques for immunosensors

A Makaraviciute, A Ramanaviciene - Biosensors and Bioelectronics, 2013 - Elsevier
Immunosensor sensitivity, regenerability, and stability directly depend on the type of
antibodies used for the immunosensor design, quantity of immobilized molecules, remaining …

Microbial tyrosinases: promising enzymes for pharmaceutical, food bioprocessing, and environmental industry

KU Zaidi, AS Ali, SA Ali, I Naaz - Biochemistry research …, 2014 - Wiley Online Library
Tyrosinase is a natural enzyme and is often purified to only a low degree and it is involved in
a variety of functions which mainly catalyse the o‐hydroxylation of monophenols into their …

Significance of antibody orientation unraveled: well-oriented antibodies recorded high binding affinity

N Tajima, M Takai, K Ishihara - Analytical chemistry, 2011 - ACS Publications
To investigate the effect of antibody orientation on its immunological activities, we developed
a novel and versatile platform consisting of a well-defined phospholipid polymer surface on …

Bacterial tyrosinases and their applications

G Faccio, K Kruus, M Saloheimo, L Thöny-Meyer - Process Biochemistry, 2012 - Elsevier
Tyrosinases with different physico-chemical properties have been identified from various
bacterial phyla such as Actinobacteria and Proteobacteria and their production is often …

Biofabrication to build the biology–device interface

Y Liu, E Kim, R Ghodssi, GW Rubloff, JN Culver… - …, 2010 - iopscience.iop.org
The last century witnessed spectacular advances in both microelectronics and
biotechnology yet there was little synergy between the two. A challenge to their integration is …

From protein features to sensing surfaces

G Faccio - Sensors, 2018 - mdpi.com
Proteins play a major role in biosensors in which they provide catalytic activity and specificity
in molecular recognition. However, the immobilization process is far from straightforward as …

Tyrosinase-mediated grafting and crosslinking of natural phenols confers functional properties to chitosan

Y Liu, B Zhang, V Javvaji, E Kim, ME Lee… - Biochemical …, 2014 - Elsevier
Physics and chemistry underpinned the remarkable advances in materials science that
occurred during the 20th century, while biology is poised to provide the scientific …