Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions
including motor control, modulation of affective and emotional states, reward mechanisms …

The most commonly used treatment for Parkinson's disease (PD) is levodopa, prescribed in
conjunction with carbidopa. Virtually all patients with PD undergo dopamine replacement …

The locus coeruleus (LC), or 'blue spot', is a small nucleus located deep in the brainstem
that provides the far-reaching noradrenergic neurotransmitter system of the brain. This …

Rats and mice are used for studying neuronal circuits underlying recognition memory due to
their ability to spontaneously remember the occurrence of an object, its place and an …

Arguably, the most difficult part of learning is deciding what to learn about. Should I
associate the positive outcome of safely completing a street-crossing with the situation 'the …

The ventral tegmental area (VTA) is well known for regulating reward consumption, learning,
memory, and addiction behaviors through mediating dopamine (DA) release in downstream …

During realistic, continuous perception, humans automatically segment experiences into
discrete events. Using a novel model of cortical event dynamics, we investigate how cortical …

Pathological alterations to the locus coeruleus, the major source of noradrenaline in the
brain, are histologically evident in early stages of neurodegenerative diseases. Novel MRI …

An organism's survival can depend on its ability to recall and navigate to spatial locations
associated with rewards, such as food or a home. Accumulating research has revealed that …

The locus coeruleus (LC) supplies norepinephrine (NE) to the entire forebrain and regulates
many fundamental brain functions. Studies in humans have suggested that strong LC …