Redox signaling: hydrogen peroxide as intracellular messenger

SG Rhee - Experimental & molecular medicine, 1999 - nature.com
Abstract Although superoxide anions (O2.-) and H2O2 are generally considered to be toxic
by-products of respiration, recent evidence suggests that the production of these reactive …

[HTML][HTML] Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose

H Ha, HB Lee - Kidney international, 2000 - Elsevier
Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under
high glucose. Background Oxidative stress is one of the important mediators of vascular …

Inorganic layered double hydroxides as nonviral vectors

JH Choy, SY Kwak, YJ Jeong… - Angewandte Chemie …, 2000 - Wiley Online Library
A biomolecular–inorganic hybrid is formed from anionic biomolecules (such as DNA
fragments, ATP, or an antisense oligonucleotide) intercalated in a cationic Mg/Al layered …

Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition

AL Kalinski, AN Kar, J Craver, AP Tosolini… - Journal of Cell …, 2019 - rupress.org
Inhibition of histone deacetylase 6 (HDAC6) was shown to support axon growth on the
nonpermissive substrates myelinassociated glycoprotein (MAG) and chondroitin sulfate …

[HTML][HTML] Platelet-derived growth factor-induced H2O2 production requires the activation of phosphatidylinositol 3-kinase

YS Bae, JY Sung, OS Kim, YJ Kim, KC Hur… - Journal of Biological …, 2000 - Elsevier
Autophosphorylation of the platelet-derived growth factor (PDGF) receptor triggers
intracellular signaling cascades as a result of recruitment of Src homology 2 domain …

Hydrogen peroxide activates p70S6k signaling pathway

GU Bae, DW Seo, HK Kwon, HY Lee, S Hong… - Journal of Biological …, 1999 - jbc.org
We investigated a possible role of reactive oxygen species (ROS) in p70 S6k activation,
which plays an important role in the progression of cells from G 0/G 1 to S phase of the cell …

Hydrogen peroxide as a diffusible signal molecule in synaptic plasticity

A Kamsler, M Segal - Molecular neurobiology, 2004 - Springer
Reactive oxygen species (ROS) have been considered for some time only in the context of
oxidative stress-induced cell damage. In this review, we discuss the growing body of …

Requirement of hydrogen peroxide generation in TGF-β1 signal transduction in human lung fibroblast cells: involvement of hydrogen peroxide and Ca2+ in TGF-β1 …

E Junn, KN Lee, HR Ju, SH Han, JY Im… - The Journal of …, 2000 - journals.aai.org
Stimulation of human lung fibroblast cells with TGF-β1 resulted in a transient burst of
reactive oxygen species with maximal increase at 5 min after treatment. This reactive oxygen …

Involvement of calcineurin in transforming growth factor-β-mediated regulation of extracellular matrix accumulation

JL Gooch, Y Gorin, BX Zhang, HE Abboud - Journal of Biological Chemistry, 2004 - jbc.org
Calcineurin is a calcium-dependent, serine/threonine phosphatase that functions as a
signaling intermediate. In this study, we investigated the role of calcineurin in transforming …

Nox family NADPH oxidases in mechano-transduction: mechanisms and consequences

RP Brandes, N Weissmann… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: The majority of cells in a multi-cellular organism are continuously exposed to
ever-changing physical forces. Mechano-transduction links these events to appropriate …