Synaptic specificity, recognition molecules, and assembly of neural circuits

JR Sanes, SL Zipursky - Cell, 2020‏ - cell.com
Develo** neurons connect in specific and stereotyped ways to form the complex circuits
that underlie brain function. By comparison to earlier steps in neural development, progress …

Expansion of the eukaryotic proteome by alternative splicing

TW Nilsen, BR Graveley - Nature, 2010‏ - nature.com
The collection of components required to carry out the intricate processes involved in
generating and maintaining a living, breathing and, sometimes, thinking organism is …

Widespread expansion of protein interaction capabilities by alternative splicing

X Yang, J Coulombe-Huntington, S Kang… - Cell, 2016‏ - cell.com
While alternative splicing is known to diversify the functional characteristics of some genes,
the extent to which protein isoforms globally contribute to functional complexity on a …

Adhesion protein structure, molecular affinities, and principles of cell-cell recognition

B Honig, L Shapiro - Cell, 2020‏ - cell.com
The ability of cells to organize into multicellular structures in precise patterns requires that
they" recognize" one another with high specificity. We discuss recent progress in …

Fc‐fusion proteins: new developments and future perspectives

DM Czajkowsky, J Hu, Z Shao… - EMBO molecular medicine, 2012‏ - embopress.org
Since the first description in 1989 of CD4‐Fc‐fusion antagonists that inhibit human immune
deficiency virus entry into T cells, Fc‐fusion proteins have been intensely investigated for …

Specification of synaptic connectivity by cell surface interactions

J De Wit, A Ghosh - Nature Reviews Neuroscience, 2016‏ - nature.com
The molecular diversification of cell surface molecules has long been postulated to impart
specific surface identities on neuronal cell types. The existence of unique cell surface …

Mechanisms and molecules of neuronal wiring: a primer

AL Kolodkin, M Tessier-Lavigne - Cold Spring Harbor …, 2011‏ - cshperspectives.cshlp.org
The complex patterns of neuronal wiring in the adult nervous system depend on a series of
guidance events during neural development that establish a framework on which functional …

Immune proteins in brain development and synaptic plasticity

LM Boulanger - Neuron, 2009‏ - cell.com
Many proteins first identified in the immune system are also expressed in the develo**
and adult nervous system. Unexpectedly, recent studies reveal that a number of these …

[ספר][B] Principles of neurobiology

L Luo - 2020‏ - taylorfrancis.com
Principles of Neurobiology, Second Edition presents the major concepts of neuroscience
with an emphasis on how we know what we know. The text is organized around a series of …

Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease

TA Ray, K Cochran, C Kozlowski, J Wang… - Nature …, 2020‏ - nature.com
Genes encoding cell-surface proteins control nervous system development and are
implicated in neurological disorders. These genes produce alternative mRNA isoforms …