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Aptamer-based detection of circulating targets for precision medicine
L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
Recent advances in SELEX technology and aptamer applications in biomedicine
Z Zhuo, Y Yu, M Wang, J Li, Z Zhang, J Liu… - International journal of …, 2017 - mdpi.com
Aptamers are short DNA/RNA oligonucleotides capable of binding to target molecules with
high affinity and specificity. The process of selecting an aptamer is called Systematic …
high affinity and specificity. The process of selecting an aptamer is called Systematic …
Aptamer-conjugated extracellular nanovesicles for targeted drug delivery
Y Wan, L Wang, C Zhu, Q Zheng, G Wang, J Tong… - Cancer …, 2018 - aacrjournals.org
Extracellular nanovesicles (ENV) released by many cells contain lipids, proteins, and
nucleic acids that contribute to intercellular communication. ENVs have emerged as …
nucleic acids that contribute to intercellular communication. ENVs have emerged as …
Aptamer in bioanalytical applications
(2009À2010), thefield of aptamer research has continuously generated lots of interest in the
scientific community. Aptamers, first reported by three groups independently in 1990, 1À3 …
scientific community. Aptamers, first reported by three groups independently in 1990, 1À3 …
Rapid magnetic isolation of extracellular vesicles via lipid-based nanoprobes
Extracellular vesicles (EVs) can mediate intercellular communication by transferring cargo
proteins and nucleic acids between cells. The pathophysiological roles and clinical value of …
proteins and nucleic acids between cells. The pathophysiological roles and clinical value of …
Selection and biosensor application of aptamers for small molecules
F Pfeiffer, G Mayer - Frontiers in chemistry, 2016 - frontiersin.org
Small molecules play a major role in the human body and as drugs, toxins, and chemicals.
Tools to detect and quantify them are therefore in high demand. This review will give an …
Tools to detect and quantify them are therefore in high demand. This review will give an …
Nucleic acid aptamers in cancer research, diagnosis and therapy
Aptamers are single-stranded DNA or RNA oligomers, identified from a random sequence
pool, with the ability to form unique and versatile tertiary structures that bind to cognate …
pool, with the ability to form unique and versatile tertiary structures that bind to cognate …
Bioinspired multivalent DNA network for capture and release of cells
Capture and isolation of flowing cells and particulates from body fluids has enormous
implications in diagnosis, monitoring, and drug testing, yet monovalent adhesion molecules …
implications in diagnosis, monitoring, and drug testing, yet monovalent adhesion molecules …
[HTML][HTML] Current approaches for avoiding the limitations of circulating tumor cells detection methods—implications for diagnosis and treatment of patients with solid …
Eight million people die of cancer each year and 90% of deaths are caused by systemic
disease. Circulating tumor cells (CTCs) contribute to the formation of metastases and thus …
disease. Circulating tumor cells (CTCs) contribute to the formation of metastases and thus …
DNA nanolithography enables a highly ordered recognition interface in a microfluidic chip for the efficient capture and release of circulating tumor cells
J Zhang, B Lin, L Wu, M Huang, X Li… - Angewandte …, 2020 - Wiley Online Library
Microfluidic chips with nano‐scale structures have shown great potential, but the fabrication
and cost issues restrict their application. Herein, we propose a conceptually new “DNA …
and cost issues restrict their application. Herein, we propose a conceptually new “DNA …