Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD)
that leads to progressive and irreversible loss of visual function. Geographic atrophy is …

Purpose: Geographic atrophy (GA) is an advanced, vision-threatening form of age-related
macular degeneration (AMD) affecting approximately five million individuals worldwide. To …

Purpose: Basal laminar deposit (BLamD) is a consistent finding in age-related macular
degeneration (AMD). We quantified BLamD thickness, appearance, and topography in eyes …

Purpose: To systematically characterize histologic features of multiple chorioretinal layers in
eyes with geographic atrophy, or complete retinal pigment epithelium (RPE) and outer …

Regulatory approval of the first two therapeutic substances for the management of
geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a major …

Purpose: To quantify organelles impacting imaging in the cell body and intact apical
processes of human retinal pigment epithelium (RPE), including melanosomes, lipofuscin …

Purpose To quantify morphological changes of the photoreceptors (PRs) and retinal pigment
epithelium (RPE) layers under pegcetacoplan therapy in geographic atrophy (GA) using …

Purpose To quantitatively measure hyperreflective foci (HRF) during the progression of
geographic atrophy (GA) secondary to age-related macular degeneration (AMD) using deep …

Purpose To perform an optical coherence tomography (OCT)-based analysis of geographic
atrophy (GA) progression in patients treated with pegcetacoplan. Design Post hoc analysis …

Age-related macular degeneration (AMD), a degenerative disorder of the central retina, is
the leading cause of irreversible blindness in the elderly. The underlying mechanism of the …