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Hyperpolarized 129Xe MRI of the human lung
By permitting direct visualization of the airspaces of the lung, magnetic resonance imaging
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …
Nuclear magnetic resonance of laser-polarized noble gases in molecules, materials, and organisms
The sensitivity of conventional nuclear magnetic resonance (NMR) techniques is
fundamentally limited by the ordinarily low spin polarization achievable in even the strongest …
fundamentally limited by the ordinarily low spin polarization achievable in even the strongest …
Hyperpolarized 3He and 129Xe MR Imaging in Healthy Volunteers and Patients with Chronic Obstructive Pulmonary Disease
Purpose To quantitatively compare hyperpolarized helium 3 (3He) and xenon 129 (129Xe)
magnetic resonance (MR) images obtained within 5 minutes in healthy volunteers and …
magnetic resonance (MR) images obtained within 5 minutes in healthy volunteers and …
Quantitative in vivo assessment of lung microstructure at the alveolar level with hyperpolarized 3He diffusion MRI
The study of lung emphysema dates back to the beginning of the 17th century. Nevertheless,
a number of important questions remain unanswered because a quantitative localized …
a number of important questions remain unanswered because a quantitative localized …
Diffusion‐weighted hyperpolarized 129Xe MRI in healthy volunteers and subjects with chronic obstructive pulmonary disease
Given its greater availability and lower cost, 129Xe apparent diffusion coefficient (ADC) MRI
offers an alternative to 3He ADC MRI. To demonstrate the feasibility of hyperpolarized …
offers an alternative to 3He ADC MRI. To demonstrate the feasibility of hyperpolarized …
Imaging of lung function using hyperpolarized helium‐3 magnetic resonance imaging: review of current and emerging translational methods and applications
During the past several years there has been extensive development and application of
hyperpolarized helium‐3 (HP 3He) magnetic resonance imaging (MRI) in clinical respiratory …
hyperpolarized helium‐3 (HP 3He) magnetic resonance imaging (MRI) in clinical respiratory …
MR imaging of diffusion of 3He gas in healthy and diseased lungs
Hyperpolarized 3He gas MRI was used to form maps of the effective diffusivity of gas in
human lungs. Images of diffusion as well as spin density are presented from a study of 11 …
human lungs. Images of diffusion as well as spin density are presented from a study of 11 …
Emphysema: hyperpolarized helium 3 diffusion MR imaging of the lungs compared with spirometric indexes—initial experience
PURPOSE: To quantitatively evaluate hyperpolarized helium 3 (3He) diffusion magnetic
resonance (MR) images of the lung in patients with emphysema and to determine whether …
resonance (MR) images of the lung in patients with emphysema and to determine whether …
Functional MRI of the lung using hyperpolarized 3‐helium gas
Lung imaging has traditionally relied on x‐ray methods, since proton MRI is limited to some
extent by low proton density in the lung parenchyma and static field inhomogeneities in the …
extent by low proton density in the lung parenchyma and static field inhomogeneities in the …
Hyperpolarized gas MRI: Technique and applications
Functional imaging today offers a rich world of information that is more sensitive to changes
in lung structure and function than traditionally obtained pulmonary function tests …
in lung structure and function than traditionally obtained pulmonary function tests …