Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that drives the
generation of myeloid cell subsets including neutrophils, monocytes, macrophages, and …

Interleukin (IL)-3 has long been known for its hematopoietic properties. However, recent
evidence has expanded our understanding of IL-3 function by identifying IL-3 as a critical …

CRISPR-Cas-based transcriptional activation (CRISPRa) and interference (CRISPRi)
enable transient programmable gene regulation by recruitment or fusion of transcriptional …

IL-3 has been reported to be involved in various inflammatory disorders, but its role in
inflammatory bowel disease (IBD) has not been addressed so far. Here, we determined IL-3 …

Importance The pathogenesis of eosinophilic cellulitis (EC) is poorly understood, limiting
available treatment options. The current treatment paradigm focuses on delayed type 2 …

Granzyme B is a renowned effector molecule primarily utilized by CTLs and NK cells against
ill-defined and/or transformed cells during immunosurveillance. The overall expression of …

ABSTRACT Polysaccharide Of Atractylodes Macrocephala Koidz (PAMK) has been proved
to have anti-cancer, antitumor, anti-inflammation function and improve the immune level of …

Colony stimulating factor 2 receptor subunit beta (CSF2RB; CD131) is the common subunit
of the type I cytokine receptors for granulocyte-macrophage colony-stimulating factor (GM …

Bovine Th2 cells have usually been characterized by IL4 mRNA expression, but it is unclear
whether their IL4 protein expression corresponds to transcription. We found that grass-fed …

Cytokines are small proteins that are critical for controlling the growth and activity of
hematopoietic cells by binding to cell surface receptors and transmitting signals across …