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Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions
C Qin, S Yang, YH Chu, H Zhang, XW Pang… - Signal transduction and …, 2022 - nature.com
Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …
severe neural injuries, and is one of the leading causes of death and disability worldwide …
Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training
B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …
exercise training are a potent stimulus for physiological adaptation in many organs …
[HTML][HTML] Naringin and naringenin: Their mechanisms of action and the potential anticancer activities
J Stabrauskiene, DM Kopustinskiene, R Lazauskas… - Biomedicines, 2022 - mdpi.com
Naringin and naringenin are the main bioactive polyphenols in citrus fruits, the consumption
of which is beneficial for human health and has been practiced since ancient times …
of which is beneficial for human health and has been practiced since ancient times …
[HTML][HTML] Autophagy: a key regulator of homeostasis and disease: an overview of molecular mechanisms and modulators
L Gómez-Virgilio, MC Silva-Lucero, DS Flores-Morelos… - Cells, 2022 - mdpi.com
Autophagy is a highly conserved lysosomal degradation pathway active at basal levels in all
cells. However, under stress conditions, such as a lack of nutrients or trophic factors, it works …
cells. However, under stress conditions, such as a lack of nutrients or trophic factors, it works …
Role of AMPK in autophagy
S Wang, H Li, M Yuan, H Fan, Z Cai - Frontiers in physiology, 2022 - frontiersin.org
Adenosine monophosphate-activated protein kinase (AMPK) is a significant energy sensor
in the maintenance of cellular energy homeostasis. Autophagy is a highly conserved …
in the maintenance of cellular energy homeostasis. Autophagy is a highly conserved …
Autophagy in liver diseases: a review
The liver is a highly dynamic metabolic organ that plays critical roles in plasma protein
synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid …
synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid …
The multifaceted role of autophagy in cancer
RC Russell, KL Guan - The EMBO journal, 2022 - embopress.org
Autophagy is a cellular degradative pathway that plays diverse roles in maintaining cellular
homeostasis. Cellular stress caused by starvation, organelle damage, or proteotoxic …
homeostasis. Cellular stress caused by starvation, organelle damage, or proteotoxic …
The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders
S Zhang, X Peng, S Yang, X Li, M Huang, S Wei… - Cell death & …, 2022 - nature.com
Autophagy is a conserved method of quality control in which cytoplasmic contents are
degraded via lysosomes. Lipophagy, a form of selective autophagy and a novel type of lipid …
degraded via lysosomes. Lipophagy, a form of selective autophagy and a novel type of lipid …
Fin56-induced ferroptosis is supported by autophagy-mediated GPX4 degradation and functions synergistically with mTOR inhibition to kill bladder cancer cells
Y Sun, N Berleth, W Wu, D Schlütermann… - Cell death & …, 2021 - nature.com
Ferroptosis is a form of regulated cell death that emerges to be relevant for therapy-resistant
and dedifferentiating cancers. Although several lines of evidence suggest that ferroptosis is …
and dedifferentiating cancers. Although several lines of evidence suggest that ferroptosis is …
[HTML][HTML] Glutamate excitotoxicity: Potential therapeutic target for ischemic stroke
Z Shen, M **ang, C Chen, F Ding, Y Wang… - Biomedicine & …, 2022 - Elsevier
Glutamate-mediated excitotoxicity is an important mechanism leading to post ischemic
stroke damage. After acute stroke, the sudden reduction in cerebral blood flow is most …
stroke damage. After acute stroke, the sudden reduction in cerebral blood flow is most …