For decades, transposable elements have been known to produce a wide variety of changes
in plant gene expression and function. This has led to the idea that transposable element …

The importance of safer approaches for gene therapy has been underscored by a series of
severe adverse events (SAEs) observed in patients involved in clinical trials for Severe …

In Darwin's and Mendel's times, researchers investigated a wealth of organisms, chosen to
solve particular problems for which they seemed especially well suited. Later, a focus on a …

The long-lasting success of forward genetic screens relies on the simple molecular basis of
the characterized phenotypes, which are typically caused by mutations in single genes …

Crop production is threatened by global climate change, and recent demands for crops to
produce bio-fuels have started to affect the worldwide supply of some of the most important …

Recent advances in plant genomics and molecular biology have revolutionized our
understanding of plant genetics, providing new opportunities for more efficient and …

CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 system, which is a
newly developed technology for targeted genome modification, has been successfully used …

Transcription activator‐like effector nuclease (TALEN) technology has been utilized widely
for targeted gene mutagenesis, especially for gene inactivation, in many organisms …

Transposable elements (TE s) are ubiquitous components of eukaryotic genomes and can
create variation in genome organization and content. Most maize genomes are composed of …

The Mu transposon system of maize is highly active, with each of the∼ 50–100 copies
transposing on average once each generation. The approximately one dozen distinct Mu …