Towards better understanding of KSHV life cycle: from transcription and posttranscriptional regulations to pathogenesis
L Yan, V Majerciak, ZM Zheng, K Lan - Virologica Sinica, 2019 - Springer
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8
(HHV-8), is etiologically linked to the development of Kaposi's sarcoma, primary effusion …
(HHV-8), is etiologically linked to the development of Kaposi's sarcoma, primary effusion …
KSHV microRNAs: tricks of the devil
J Qin, W Li, SJ Gao, C Lu - Trends in microbiology, 2017 - cell.com
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma
(KS), a vascular tumor frequently found in immunodeficient individuals. KSHV encodes 12 …
(KS), a vascular tumor frequently found in immunodeficient individuals. KSHV encodes 12 …
N6-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated …
Methylation at the N 6 position of adenosine (m6A) is a highly prevalent and reversible
modification within eukaryotic mRNAs that has been linked to many stages of RNA …
modification within eukaryotic mRNAs that has been linked to many stages of RNA …
Inhibition of cGAS DNA sensing by a herpesvirus virion protein
Invading viral DNA can be recognized by the host cytosolic DNA sensor, cyclic GMP-AMP
(cGAMP) synthase (cGAS), resulting in production of the second messenger cGAMP, which …
(cGAMP) synthase (cGAS), resulting in production of the second messenger cGAMP, which …
Viral and cellular N6-methyladenosine and N6,2′-O-dimethyladenosine epitranscriptomes in the KSHV life cycle
Abstract N6-methyladenosine (m6A) and N6, 2′-O-dimethyladenosine (m6Am)
modifications (m6A/m) of messenger RNA mediate diverse cellular functions. Oncogenic …
modifications (m6A/m) of messenger RNA mediate diverse cellular functions. Oncogenic …
Global map** of herpesvirus-host protein complexes reveals a transcription strategy for late genes
Map** host-pathogen interactions has proven instrumental for understanding how viruses
manipulate host machinery and how numerous cellular processes are regulated. DNA …
manipulate host machinery and how numerous cellular processes are regulated. DNA …
High-throughput RNA sequencing of paraformaldehyde-fixed single cells
Single-cell transcriptomic studies that require intracellular protein staining, rare cell sorting,
or inactivation of infectious pathogens are severely limited. This is because current high …
or inactivation of infectious pathogens are severely limited. This is because current high …
Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N6-Adenosine Methylation To Promote Lytic Replication
F Ye, ER Chen, TW Nilsen - Journal of virology, 2017 - Am Soc Microbiol
ABSTRACT N6-adenosine methylation (m6A) is the most common posttranscriptional RNA
modification in mammalian cells. We found that most transcripts encoded by the Kaposi's …
modification in mammalian cells. We found that most transcripts encoded by the Kaposi's …
KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
A Kumar, Y Lyu, Y Yanagihashi, C Chantarasrivong… - Cell reports, 2022 - cell.com
Kaposi sarcoma-associated herpesvirus (KSHV) establishes a latent infection in the cell
nucleus, but where KSHV episomal genomes are tethered and the mechanisms underlying …
nucleus, but where KSHV episomal genomes are tethered and the mechanisms underlying …
The mitophagy receptor NIX induces vIRF-1 oligomerization and interaction with GABARAPL1 for the promotion of HHV-8 reactivation-induced mitophagy
Recently, viruses have been shown to regulate selective autophagy for productive
infections. For instance, human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma …
infections. For instance, human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma …