Mesenchymal stem cell (MSC)-derived secretome demonstrated therapeutic effects like
those reported after MSCs transplantation. MSC-derived secretome may avoid various side …

Parkinson's disease (PD) is a progressively debilitating neurodegenerative condition that
leads to motor and cognitive dysfunction. At present, clinical treatment can only improve …

An increase in life expectancy comes with a higher risk for age-related neurological and
cognitive dysfunctions. Given the psycho-socioeconomic burden due to unhealthy aging in …

Wound healing is a dynamic and complex process that contains several sequential phases.
However, most of the current drug delivery systems were designed to treat only one certain …

Parkinson's disease (PD) is characterized by a selective loss of dopamine (DA) neurons in
the human midbrain causing motor dysfunctions. The exact mechanism behind …

Stem cells offer the basis for the promotion of robust new therapeutic approaches for a
variety of human disorders. There are still many limitations to be overcome before clinical …

Neurodegenerative disorders are characterized by complex multifactorial pathogeneses,
thus posing a challenge for standard therapeutic approaches that tend to focus only on one …

Spinocerebellar ataxias are heritable neurodegenerative diseases caused by a cytosine-
adenine-guanine expansion, which encodes a long glutamine tract (polyglutamine) in the …

Parkinson's disease (PD) is the second most prevalent neurodegenerative disease
characterized by severe dyskinesia due to a progressive loss of dopaminergic neurons …

Applying stem cell therapy in intractable diseases: a narrative review of decades of progress
and challenges - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …